Difference between revisions of "YMR032W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004635 YMR032W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HOF1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HOF1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XIII: | + | |nowrap| Chr XIII:335298..337307 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004635 | ||
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| − | '''Description of | + | '''Description of YMR032W:''' Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p<ref name='S000053897'>Kamei T, et al. (1998) Interaction of Bnr1p with a novel Src homology 3 domain-containing Hof1p. Implication in cytokinesis in Saccharomyces cerevisiae. J Biol Chem 273(43):28341-5 {{SGDpaper|S000053897}} PMID 9774458</ref><ref name='S000059205'>Korinek WS, et al. (2000) Cyk3, a novel SH3-domain protein, affects cytokinesis in yeast. Curr Biol 10(15):947-50 {{SGDpaper|S000059205}} PMID 10959846</ref><ref name='S000071355'>Lee PR, et al. (2002) Bni5p, a septin-interacting protein, is required for normal septin function and cytokinesis in Saccharomyces cerevisiae. Mol Cell Biol 22(19):6906-20 {{SGDpaper|S000071355}} PMID 12215547</ref><ref name='S000055446'>Lippincott J and Li R (1998) Dual function of Cyk2, a cdc15/PSTPIP family protein, in regulating actomyosin ring dynamics and septin distribution. J Cell Biol 143(7):1947-60 {{SGDpaper|S000055446}} PMID 9864366</ref><ref name='S000060060'>Naqvi SN, et al. (2001) Vrp1p functions in both actomyosin ring-dependent and Hof1p-dependent pathways of cytokinesis. Traffic 2(3):189-201 |
| − | {{SGDpaper| | + | {{SGDpaper|S000060060}} PMID 11260524</ref> |
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YMR032W |
| Gene name | HOF1 |
| Aliases | CYK2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:335298..337307 |
| Primary SGDID | S000004635 |
Description of YMR032W: Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p[1][2][3][4][5]
</protect>
Community Commentary
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Interactions
Genetic
Genetic interaction with myo1
Phenotype(s): Synthetic Lethal with myo1
Mutation type(s): deletion, deletion
[6] [7]
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References
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- ↑ Kamei T, et al. (1998) Interaction of Bnr1p with a novel Src homology 3 domain-containing Hof1p. Implication in cytokinesis in Saccharomyces cerevisiae. J Biol Chem 273(43):28341-5 SGD PMID 9774458
- ↑ Korinek WS, et al. (2000) Cyk3, a novel SH3-domain protein, affects cytokinesis in yeast. Curr Biol 10(15):947-50 SGD PMID 10959846
- ↑ Lee PR, et al. (2002) Bni5p, a septin-interacting protein, is required for normal septin function and cytokinesis in Saccharomyces cerevisiae. Mol Cell Biol 22(19):6906-20 SGD PMID 12215547
- ↑ Lippincott J and Li R (1998) Dual function of Cyk2, a cdc15/PSTPIP family protein, in regulating actomyosin ring dynamics and septin distribution. J Cell Biol 143(7):1947-60 SGD PMID 9864366
- ↑ Naqvi SN, et al. (2001) Vrp1p functions in both actomyosin ring-dependent and Hof1p-dependent pathways of cytokinesis. Traffic 2(3):189-201 SGD PMID 11260524
- ↑ Vallen EA, et al. (2000) Roles of Hof1p, Bni1p, Bnr1p, and myo1p in cytokinesis in Saccharomyces cerevisiae. Mol Biol Cell 11(2):593-611 SGD PMID 10679017
- ↑ submitted by Erfei Bi on 2003-08-14
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