YMR032W
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| Systematic name | YMR032W |
| Gene name | HOF1 |
| Aliases | CYK2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:335298..337307 |
| Primary SGDID | S000004635 |
Description of YMR032W: Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p[1][2][3][4][5]
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Community Commentary
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Interactions
Genetic
Genetic interaction with myo1
Phenotype(s): Synthetic Lethal with myo1
Mutation type(s): deletion, deletion
[6] [7]
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References
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- ↑ Kamei T, et al. (1998) Interaction of Bnr1p with a novel Src homology 3 domain-containing Hof1p. Implication in cytokinesis in Saccharomyces cerevisiae. J Biol Chem 273(43):28341-5 SGD PMID 9774458
- ↑ Korinek WS, et al. (2000) Cyk3, a novel SH3-domain protein, affects cytokinesis in yeast. Curr Biol 10(15):947-50 SGD PMID 10959846
- ↑ Lee PR, et al. (2002) Bni5p, a septin-interacting protein, is required for normal septin function and cytokinesis in Saccharomyces cerevisiae. Mol Cell Biol 22(19):6906-20 SGD PMID 12215547
- ↑ Lippincott J and Li R (1998) Dual function of Cyk2, a cdc15/PSTPIP family protein, in regulating actomyosin ring dynamics and septin distribution. J Cell Biol 143(7):1947-60 SGD PMID 9864366
- ↑ Naqvi SN, et al. (2001) Vrp1p functions in both actomyosin ring-dependent and Hof1p-dependent pathways of cytokinesis. Traffic 2(3):189-201 SGD PMID 11260524
- ↑ Vallen EA, et al. (2000) Roles of Hof1p, Bni1p, Bnr1p, and myo1p in cytokinesis in Saccharomyces cerevisiae. Mol Biol Cell 11(2):593-611 SGD PMID 10679017
- ↑ submitted by Erfei Bi on 2003-08-14
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