Difference between revisions of "YLR234W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004224 YLR234W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TOP3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TOP3 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XII: | + | |nowrap| Chr XII:609783..611753 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004224 | ||
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| − | '''Description of | + | '''Description of YLR234W:''' DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination<ref name='S000045002'>Bailis AM, et al. (1992) Genome rearrangement in top3 mutants of Saccharomyces cerevisiae requires a functional RAD1 excision repair gene. Mol Cell Biol 12(11):4988-93 {{SGDpaper|S000045002}} PMID 1328869</ref><ref name='S000040232'>Bennett RJ, et al. (2000) Interaction between yeast sgs1 helicase and DNA topoisomerase III. J Biol Chem 275(35):26898-905 {{SGDpaper|S000040232}} PMID 10862619</ref><ref name='S000081006'>Chang M, et al. (2005) RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J 24(11):2024-33 {{SGDpaper|S000081006}} PMID 15889139</ref><ref name='S000056212'>Kim RA and Wang JC (1992) Identification of the yeast TOP3 gene product as a single strand-specific DNA topoisomerase. J Biol Chem 267(24):17178-85 {{SGDpaper|S000056212}} PMID 1324925</ref><ref name='S000039158'>Kim RA, et al. (1995) Effects of yeast DNA topoisomerase III on telomere structure. Proc Natl Acad Sci U S A 92(7):2667-71 |
{{SGDpaper|S000039158}} PMID 7708702</ref> | {{SGDpaper|S000039158}} PMID 7708702</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YLR234W |
| Gene name | TOP3 |
| Aliases | EDR1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:609783..611753 |
| Primary SGDID | S000004224 |
Description of YLR234W: DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination[1][2][3][4][5]
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References
See Help:References on how to add references
- ↑ Bailis AM, et al. (1992) Genome rearrangement in top3 mutants of Saccharomyces cerevisiae requires a functional RAD1 excision repair gene. Mol Cell Biol 12(11):4988-93 SGD PMID 1328869
- ↑ Bennett RJ, et al. (2000) Interaction between yeast sgs1 helicase and DNA topoisomerase III. J Biol Chem 275(35):26898-905 SGD PMID 10862619
- ↑ Chang M, et al. (2005) RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J 24(11):2024-33 SGD PMID 15889139
- ↑ Kim RA and Wang JC (1992) Identification of the yeast TOP3 gene product as a single strand-specific DNA topoisomerase. J Biol Chem 267(24):17178-85 SGD PMID 1324925
- ↑ Kim RA, et al. (1995) Effects of yeast DNA topoisomerase III on telomere structure. Proc Natl Acad Sci U S A 92(7):2667-71 SGD PMID 7708702
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