Difference between revisions of "YJR024C"
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{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003785 YJR024C] |
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||'' '' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MDE1 '' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' '' | ||
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr X: | + | |nowrap| Chr X:470964..470230 |
+ | |- | ||
+ | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003785 | ||
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<br> | <br> | ||
− | '''Description of | + | '''Description of YJR024C:''' 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant<ref name='S000076477'>Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 {{SGDpaper|S000076477}} PMID 15166135</ref><ref name='S000079733'>Panse VG, et al. (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279(40):41346-51 {{SGDpaper|S000079733}} PMID 15292183</ref><ref name='S000127022'>Pirkov I, et al. (2008) A complete inventory of all enzymes in the eukaryotic methionine salvage pathway. FEBS J 275(16):4111-20 {{SGDpaper|S000127022}} PMID 18625006</ref><ref name='S000075217'>Reinoso-Martin C, et al. (2003) The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot Cell 2(6):1200-10 {{SGDpaper|S000075217}} PMID 14665455</ref><ref name='S000122946'>Sekowska A, et al. (2004) Bacterial variations on the methionine salvage pathway. BMC Microbiol 4():9 |
− | {{SGDpaper| | + | {{SGDpaper|S000122946}} PMID 15102328</ref> |
<br> | <br> | ||
<br> | <br> | ||
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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+ | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YJR024C |
Gene name | MDE1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr X:470964..470230 |
Primary SGDID | S000003785 |
Description of YJR024C: 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant[1][2][3][4][5]
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References
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- ↑ Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 SGD PMID 15166135
- ↑ Panse VG, et al. (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279(40):41346-51 SGD PMID 15292183
- ↑ Pirkov I, et al. (2008) A complete inventory of all enzymes in the eukaryotic methionine salvage pathway. FEBS J 275(16):4111-20 SGD PMID 18625006
- ↑ Reinoso-Martin C, et al. (2003) The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot Cell 2(6):1200-10 SGD PMID 14665455
- ↑ Sekowska A, et al. (2004) Bacterial variations on the methionine salvage pathway. BMC Microbiol 4():9 SGD PMID 15102328
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