Difference between revisions of "YIR006C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001445 YIR006C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PAN1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PAN1 '' | ||
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| − | '''Description of YIR006C:''' Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on the cell cortex; promotes protein-protein interactions essential for endocytosis; previously thought to be a subunit of poly(A) ribonuclease<ref name='S000043462'>Tang HY and Cai M (1996) The EH-domain-containing protein Pan1 is required for normal organization of the actin cytoskeleton in Saccharomyces cerevisiae. Mol Cell Biol 16(9):4897-914 {{SGDpaper|S000043462}} PMID 8756649</ref><ref name='S000048205'>Wendland B, et al. (1996) A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15. J Cell Biol 135(6 Pt 1):1485-500 {{SGDpaper|S000048205}} PMID 8978817</ref><ref name='S000069873'>Zeng G, et al. (2001) Regulation of yeast actin cytoskeleton-regulatory complex Pan1p/Sla1p/End3p by serine/threonine kinase Prk1p. Mol Biol Cell 12(12):3759-72 | + | '''Description of YIR006C:''' Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on the cell cortex; promotes protein-protein interactions essential for endocytosis; binds to and activates the Arp2/3 complex in vitro; previously thought to be a subunit of poly(A) ribonuclease<ref name='S000086571'>Duncan MC, et al. (2001) Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex. Nat Cell Biol 3(7):687-90 {{SGDpaper|S000086571}} PMID 11433303</ref><ref name='S000043462'>Tang HY and Cai M (1996) The EH-domain-containing protein Pan1 is required for normal organization of the actin cytoskeleton in Saccharomyces cerevisiae. Mol Cell Biol 16(9):4897-914 {{SGDpaper|S000043462}} PMID 8756649</ref><ref name='S000048205'>Wendland B, et al. (1996) A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15. J Cell Biol 135(6 Pt 1):1485-500 {{SGDpaper|S000048205}} PMID 8978817</ref><ref name='S000069873'>Zeng G, et al. (2001) Regulation of yeast actin cytoskeleton-regulatory complex Pan1p/Sla1p/End3p by serine/threonine kinase Prk1p. Mol Biol Cell 12(12):3759-72 |
{{SGDpaper|S000069873}} PMID 11739778</ref> | {{SGDpaper|S000069873}} PMID 11739778</ref> | ||
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YIR006C |
| Gene name | PAN1 |
| Aliases | DIM2, MDP3, MIP3 |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:369908..365466 |
| Primary SGDID | S000001445 |
Description of YIR006C: Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on the cell cortex; promotes protein-protein interactions essential for endocytosis; binds to and activates the Arp2/3 complex in vitro; previously thought to be a subunit of poly(A) ribonuclease[1][2][3][4]
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References
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- ↑ Duncan MC, et al. (2001) Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex. Nat Cell Biol 3(7):687-90 SGD PMID 11433303
- ↑ Tang HY and Cai M (1996) The EH-domain-containing protein Pan1 is required for normal organization of the actin cytoskeleton in Saccharomyces cerevisiae. Mol Cell Biol 16(9):4897-914 SGD PMID 8756649
- ↑ Wendland B, et al. (1996) A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15. J Cell Biol 135(6 Pt 1):1485-500 SGD PMID 8978817
- ↑ Zeng G, et al. (2001) Regulation of yeast actin cytoskeleton-regulatory complex Pan1p/Sla1p/End3p by serine/threonine kinase Prk1p. Mol Biol Cell 12(12):3759-72 SGD PMID 11739778
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