Difference between revisions of "YJR066W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003827 YJR066W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TOR1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TOR1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr X: | + | |nowrap| Chr X:559416..566828 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003827 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003827 | ||
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| − | '''Description of YJR066W:''' PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis<ref name='S000050240'>Barbet NC, et al. (1996) TOR controls translation initiation and early G1 progression in yeast. Mol Biol Cell 7(1):25-42 {{SGDpaper|S000050240}} PMID 8741837</ref><ref name='S000046200'>Beck T and Hall MN (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402(6762):689-92 {{SGDpaper|S000046200}} PMID 10604478</ref><ref name='S000055222'>Cardenas ME, et al. (1999) The TOR signaling cascade regulates gene expression in response to nutrients. Genes Dev 13(24):3271-9 {{SGDpaper|S000055222}} PMID 10617575</ref><ref name='S000042312'>Kamada Y, et al. (2000) Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 150(6):1507-13 {{SGDpaper|S000042312}} PMID 10995454</ref><ref name='S000071528'>Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68 {{SGDpaper|S000071528}} PMID 12408816</ref><ref name='S000077468'>Lorberg A and Hall MN (2004) TOR: the first 10 years. Curr Top Microbiol Immunol 279:1-18 {{SGDpaper|S000077468}} PMID 14560948</ref><ref name='S000080060'>Martin DE, et al. (2004) TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell 119(7):969-79 {{SGDpaper|S000080060}} PMID 15620355</ref><ref name='S000053128'>Powers T and Walter P (1999) Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol Biol Cell 10(4):987-1000 {{SGDpaper|S000053128}} PMID 10198052</ref><ref name='S000071617'>Torres J, et al. (2002) Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast. J Biol Chem 277(45):43495-504 {{SGDpaper|S000071617}} PMID 12171921</ref><ref name='S000041984'>Zheng XF and Schreiber SL (1997) Target of rapamycin proteins and their kinase activities are required for meiosis. Proc Natl Acad Sci U S A 94(7):3070-5 | + | '''Description of YJR066W:''' PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis<ref name='S000050240'>Barbet NC, et al. (1996) TOR controls translation initiation and early G1 progression in yeast. Mol Biol Cell 7(1):25-42 {{SGDpaper|S000050240}} PMID 8741837</ref><ref name='S000046200'>Beck T and Hall MN (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402(6762):689-92 {{SGDpaper|S000046200}} PMID 10604478</ref><ref name='S000055222'>Cardenas ME, et al. (1999) The TOR signaling cascade regulates gene expression in response to nutrients. Genes Dev 13(24):3271-9 {{SGDpaper|S000055222}} PMID 10617575</ref><ref name='S000042312'>Kamada Y, et al. (2000) Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 150(6):1507-13 {{SGDpaper|S000042312}} PMID 10995454</ref><ref name='S000071528'>Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68 {{SGDpaper|S000071528}} PMID 12408816</ref><ref name='S000077468'>Lorberg A and Hall MN (2004) TOR: the first 10 years. Curr Top Microbiol Immunol 279():1-18 {{SGDpaper|S000077468}} PMID 14560948</ref><ref name='S000080060'>Martin DE, et al. (2004) TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell 119(7):969-79 {{SGDpaper|S000080060}} PMID 15620355</ref><ref name='S000053128'>Powers T and Walter P (1999) Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol Biol Cell 10(4):987-1000 {{SGDpaper|S000053128}} PMID 10198052</ref><ref name='S000071617'>Torres J, et al. (2002) Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast. J Biol Chem 277(45):43495-504 {{SGDpaper|S000071617}} PMID 12171921</ref><ref name='S000041984'>Zheng XF and Schreiber SL (1997) Target of rapamycin proteins and their kinase activities are required for meiosis. Proc Natl Acad Sci U S A 94(7):3070-5 |
{{SGDpaper|S000041984}} PMID 9096347</ref> | {{SGDpaper|S000041984}} PMID 9096347</ref> | ||
<br> | <br> | ||
Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YJR066W |
| Gene name | TOR1 |
| Aliases | DRR1 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:559416..566828 |
| Primary SGDID | S000003827 |
Description of YJR066W: PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis[1][2][3][4][5][6][7][8][9][10]
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Interactions
Regulatory
Regulatory interaction with YBL064c
PRX1 mRNA expression is down regulated by TOR1p in the presence of glucose. [11] [12]
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References
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- ↑ Barbet NC, et al. (1996) TOR controls translation initiation and early G1 progression in yeast. Mol Biol Cell 7(1):25-42 SGD PMID 8741837
- ↑ Beck T and Hall MN (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402(6762):689-92 SGD PMID 10604478
- ↑ Cardenas ME, et al. (1999) The TOR signaling cascade regulates gene expression in response to nutrients. Genes Dev 13(24):3271-9 SGD PMID 10617575
- ↑ Kamada Y, et al. (2000) Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 150(6):1507-13 SGD PMID 10995454
- ↑ Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68 SGD PMID 12408816
- ↑ Lorberg A and Hall MN (2004) TOR: the first 10 years. Curr Top Microbiol Immunol 279():1-18 SGD PMID 14560948
- ↑ Martin DE, et al. (2004) TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell 119(7):969-79 SGD PMID 15620355
- ↑ Powers T and Walter P (1999) Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol Biol Cell 10(4):987-1000 SGD PMID 10198052
- ↑ Torres J, et al. (2002) Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast. J Biol Chem 277(45):43495-504 SGD PMID 12171921
- ↑ Zheng XF and Schreiber SL (1997) Target of rapamycin proteins and their kinase activities are required for meiosis. Proc Natl Acad Sci U S A 94(7):3070-5 SGD PMID 9096347
- ↑ Monteiro G and Netto LE (2004) Glucose repression of PRX1 expression is mediated by Tor1p and Ras2p through inhibition of Msn2/4p in Saccharomyces cerevisiae. FEMS Microbiol Lett 241(2):221-8 SGD PMID 15598536
- ↑ submitted by Gisele Monteiro on 2005-01-03
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