Difference between revisions of "YMR032W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YMR032W YMR032W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004635 YMR032W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HOF1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HOF1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIII:335297..337306
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|nowrap| Chr XIII:335298..337307
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004635
 
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'''Description of {{PAGENAME}}:''' Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p<ref name='S000071355'>Lee PR, et al. (2002) Bni5p, a septin-interacting protein, is required for normal septin function and cytokinesis in Saccharomyces cerevisiae. Mol Cell Biol 22(19):6906-20 {{SGDpaper|S000071355}} PMID 12215547</ref><ref name='S000060060'>Naqvi SN, et al. (2001) Vrp1p functions in both actomyosin ring-dependent and Hof1p-dependent pathways of cytokinesis. Traffic 2(3):189-201 {{SGDpaper|S000060060}} PMID 11260524</ref><ref name='S000059205'>Korinek WS, et al. (2000) Cyk3, a novel SH3-domain protein, affects cytokinesis in yeast. Curr Biol 10(15):947-50 {{SGDpaper|S000059205}} PMID 10959846</ref><ref name='S000055446'>Lippincott J and Li R (1998) Dual function of Cyk2, a cdc15/PSTPIP family protein, in regulating actomyosin ring dynamics and septin distribution. J Cell Biol 143(7):1947-60 {{SGDpaper|S000055446}} PMID 9864366</ref><ref name='S000053897'>Kamei T, et al. (1998) Interaction of Bnr1p with a novel Src homology 3 domain-containing Hof1p. Implication in cytokinesis in Saccharomyces cerevisiae. J Biol Chem 273(43):28341-5
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'''Description of YMR032W:''' Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p<ref name='S000053897'>Kamei T, et al. (1998) Interaction of Bnr1p with a novel Src homology 3 domain-containing Hof1p. Implication in cytokinesis in Saccharomyces cerevisiae. J Biol Chem 273(43):28341-5 {{SGDpaper|S000053897}} PMID 9774458</ref><ref name='S000059205'>Korinek WS, et al. (2000) Cyk3, a novel SH3-domain protein, affects cytokinesis in yeast. Curr Biol 10(15):947-50 {{SGDpaper|S000059205}} PMID 10959846</ref><ref name='S000071355'>Lee PR, et al. (2002) Bni5p, a septin-interacting protein, is required for normal septin function and cytokinesis in Saccharomyces cerevisiae. Mol Cell Biol 22(19):6906-20 {{SGDpaper|S000071355}} PMID 12215547</ref><ref name='S000055446'>Lippincott J and Li R (1998) Dual function of Cyk2, a cdc15/PSTPIP family protein, in regulating actomyosin ring dynamics and septin distribution. J Cell Biol 143(7):1947-60 {{SGDpaper|S000055446}} PMID 9864366</ref><ref name='S000060060'>Naqvi SN, et al. (2001) Vrp1p functions in both actomyosin ring-dependent and Hof1p-dependent pathways of cytokinesis. Traffic 2(3):189-201
  {{SGDpaper|S000053897}} PMID 9774458</ref>
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  {{SGDpaper|S000060060}} PMID 11260524</ref>
 
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=== Interactions ===
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[[Category:Topic:Interactions]]
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==== Genetic ====
 
[[Category:Topic:Interactions:Genetic]]
 
Genetic interaction with myo1 [[Category:Genetic Interactions with myo1]]<br>'''Phenotype(s)''': Synthetic Lethal with myo1 [[Category:Phenotype:Synthetic Lethal with myo1]]
 
'''Mutation type(s)''': deletion, deletion
 
<ref name='S000040799'>Vallen EA, et al. (2000) Roles of Hof1p, Bni1p, Bnr1p, and myo1p in cytokinesis in Saccharomyces cerevisiae. Mol Biol Cell 11(2):593-611 {{SGDpaper|S000040799}} PMID 10679017</ref> <ref name = 'CAset448-2003-08-14'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=448 Erfei Bi] on 2003-08-14</ref>
 
 
 
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==Community Commentary==
 
==Community Commentary==
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YMR032W
Gene name HOF1
Aliases CYK2
Feature type ORF, Verified
Coordinates Chr XIII:335298..337307
Primary SGDID S000004635


Description of YMR032W: Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p[1][2][3][4][5]




</protect>

Community Commentary

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Interactions

Genetic

Genetic interaction with myo1
Phenotype(s): Synthetic Lethal with myo1 Mutation type(s): deletion, deletion

[6] [7]




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References

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  1. Kamei T, et al. (1998) Interaction of Bnr1p with a novel Src homology 3 domain-containing Hof1p. Implication in cytokinesis in Saccharomyces cerevisiae. J Biol Chem 273(43):28341-5 SGD PMID 9774458
  2. Korinek WS, et al. (2000) Cyk3, a novel SH3-domain protein, affects cytokinesis in yeast. Curr Biol 10(15):947-50 SGD PMID 10959846
  3. Lee PR, et al. (2002) Bni5p, a septin-interacting protein, is required for normal septin function and cytokinesis in Saccharomyces cerevisiae. Mol Cell Biol 22(19):6906-20 SGD PMID 12215547
  4. Lippincott J and Li R (1998) Dual function of Cyk2, a cdc15/PSTPIP family protein, in regulating actomyosin ring dynamics and septin distribution. J Cell Biol 143(7):1947-60 SGD PMID 9864366
  5. Naqvi SN, et al. (2001) Vrp1p functions in both actomyosin ring-dependent and Hof1p-dependent pathways of cytokinesis. Traffic 2(3):189-201 SGD PMID 11260524
  6. Vallen EA, et al. (2000) Roles of Hof1p, Bni1p, Bnr1p, and myo1p in cytokinesis in Saccharomyces cerevisiae. Mol Biol Cell 11(2):593-611 SGD PMID 10679017
  7. submitted by Erfei Bi on 2003-08-14

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