Difference between revisions of "YLR193C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004183 YLR193C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''UPS1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''UPS1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XII: | + | |nowrap| Chr XII:540536..540009 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004183 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004183 | ||
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| − | '''Description of YLR193C:''' Mitochondrial intermembrane space | + | '''Description of YLR193C:''' Mitochondrial protein involved in phospholipid metabolism; localizes to the intermembrane space; has a role in regulation of phospholipid metabolism by promoting conversion of phosphatidylethanolamine to phosphatidylcholine; null mutant has altered cardiolipin and phosphatidylethanolamine levels and defects in Mgm1p processing, integrity of mitochondrial inner membrane complexes, and mitochondrial morphology; ortholog of human PRELI<ref name='S000129376'>Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 {{SGDpaper|S000129376}} PMID 19221197</ref><ref name='S000116292'>Sesaki H, et al. (2006) Ups1p, a conserved intermembrane space protein, regulates mitochondrial shape and alternative topogenesis of Mgm1p. J Cell Biol 173(5):651-8 {{SGDpaper|S000116292}} PMID 16754953</ref><ref name='S000130717'>Tamura Y, et al. (2009) Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria. J Cell Biol 185(6):1029-45 {{SGDpaper|S000130717}} PMID 19506038</ref><ref name='S000148784'>Tamura Y, et al. (2012) Role for two conserved intermembrane space proteins, Ups1p and Up2p, in intra-mitochondrial phospholipid trafficking. J Biol Chem () |
| − | {{SGDpaper| | + | {{SGDpaper|S000148784}} PMID 22403410</ref> |
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Latest revision as of 13:05, 23 March 2012
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| Systematic name | YLR193C |
| Gene name | UPS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:540536..540009 |
| Primary SGDID | S000004183 |
Description of YLR193C: Mitochondrial protein involved in phospholipid metabolism; localizes to the intermembrane space; has a role in regulation of phospholipid metabolism by promoting conversion of phosphatidylethanolamine to phosphatidylcholine; null mutant has altered cardiolipin and phosphatidylethanolamine levels and defects in Mgm1p processing, integrity of mitochondrial inner membrane complexes, and mitochondrial morphology; ortholog of human PRELI[1][2][3][4]
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References
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- ↑ Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 SGD PMID 19221197
- ↑ Sesaki H, et al. (2006) Ups1p, a conserved intermembrane space protein, regulates mitochondrial shape and alternative topogenesis of Mgm1p. J Cell Biol 173(5):651-8 SGD PMID 16754953
- ↑ Tamura Y, et al. (2009) Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria. J Cell Biol 185(6):1029-45 SGD PMID 19506038
- ↑ Tamura Y, et al. (2012) Role for two conserved intermembrane space proteins, Ups1p and Up2p, in intra-mitochondrial phospholipid trafficking. J Biol Chem () SGD PMID 22403410
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