Difference between revisions of "YLR240W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004230 YLR240W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS34 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS34 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XII: | + | |nowrap| Chr XII:617533..620160 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004230 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004230 | ||
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| − | '''Description of YLR240W:''' Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p<ref name='S000048206'>Herman PK and Emr SD (1990) Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell Biol 10(12):6742-54 {{SGDpaper|S000048206}} PMID 2247081</ref><ref name=' | + | '''Description of YLR240W:''' Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p<ref name='S000073406'>Burda P, et al. (2002) Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase. J Cell Sci 115(Pt 20):3889-900 {{SGDpaper|S000073406}} PMID 12244127</ref><ref name='S000048206'>Herman PK and Emr SD (1990) Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell Biol 10(12):6742-54 {{SGDpaper|S000048206}} PMID 2247081</ref><ref name='S000117071'>Slessareva JE, et al. (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. Cell 126(1):191-203 {{SGDpaper|S000117071}} PMID 16839886</ref><ref name='S000052180'>Stack JH, et al. (1993) A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole. EMBO J 12(5):2195-204 |
| − | {{SGDpaper| | + | {{SGDpaper|S000052180}} PMID 8387919</ref> |
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YLR240W |
| Gene name | VPS34 |
| Aliases | END12, PEP15, STT8, VPL7, VPS7, VPT29 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:617533..620160 |
| Primary SGDID | S000004230 |
Description of YLR240W: Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p[1][2][3][4]
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References
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- ↑ Burda P, et al. (2002) Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase. J Cell Sci 115(Pt 20):3889-900 SGD PMID 12244127
- ↑ Herman PK and Emr SD (1990) Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell Biol 10(12):6742-54 SGD PMID 2247081
- ↑ Slessareva JE, et al. (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. Cell 126(1):191-203 SGD PMID 16839886
- ↑ Stack JH, et al. (1993) A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole. EMBO J 12(5):2195-204 SGD PMID 8387919
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