Difference between revisions of "YCL067C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000572 YCL067C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HMLALPHA2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HMLALPHA2 '' | ||
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| − | '''Description of YCL067C:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression | + | '''Description of YCL067C:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82 {{SGDpaper|S000044255}} PMID 3127056</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000058493}} PMID </ref><ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 |
| − | {{SGDpaper| | + | {{SGDpaper|S000051804}} PMID 10568744</ref> |
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YCL067C |
| Gene name | HMLALPHA2 |
| Aliases | ALPHA2 |
| Feature type | ORF, silenced_gene,Verified |
| Coordinates | Chr III:13018..12386 |
| Primary SGDID | S000000572 |
Description of YCL067C: Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression[1][2][3][4][5][6][7][8][9]
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References
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- ↑ Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82 SGD PMID 3127056
- ↑ Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 SGD PMID 8411150
- ↑ Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 SGD PMID 7907979
- ↑ Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 SGD PMID 2513489
- ↑ Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press SGD PMID
- ↑ Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 SGD PMID 8341604
- ↑ Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 SGD PMID 1732062
- ↑ Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 SGD PMID 8422672
- ↑ Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 SGD PMID 10568744
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