Difference between revisions of "YPL101W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006022 YPL101W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006022 YPL101W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ELP4 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ELP4 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XVI:360206..361576
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|nowrap| Chr XVI:360209..361579
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006022
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006022
 
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'''Description of YPL101W:''' Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity<ref name='S000119100'>Esberg A, et al. (2006) Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis. Mol Cell 24(1):139-48 {{SGDpaper|S000119100}} PMID 17018299</ref><ref name='S000072244'>Frohloff F, et al. (2003) Subunit communications crucial for the functional integrity of the yeast RNA polymerase II elongator (gamma-toxin target (TOT)) complex. J Biol Chem 278(2):956-61 {{SGDpaper|S000072244}} PMID 12424236</ref><ref name='S000069595'>Winkler GS, et al. (2002) Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo. Proc Natl Acad Sci U S A 99(6):3517-22
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'''Description of YPL101W:''' Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity<ref name='S000119100'>Esberg A, et al. (2006) Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis. Mol Cell 24(1):139-48 {{SGDpaper|S000119100}} PMID 17018299</ref><ref name='S000072244'>Frohloff F, et al. (2003) Subunit communications crucial for the functional integrity of the yeast RNA polymerase II elongator (gamma-toxin target (TOT)) complex. J Biol Chem 278(2):956-61 {{SGDpaper|S000072244}} PMID 12424236</ref><ref name='S000148498'>Glatt S, et al. (2012) The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase.LID - 10.1038/nsmb.2234 [doi] Nat Struct Mol Biol () {{SGDpaper|S000148498}} PMID 22343726</ref><ref name='S000069595'>Winkler GS, et al. (2002) Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo. Proc Natl Acad Sci U S A 99(6):3517-22
 
  {{SGDpaper|S000069595}} PMID 11904415</ref>
 
  {{SGDpaper|S000069595}} PMID 11904415</ref>
 
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Latest revision as of 13:05, 7 March 2012

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Systematic name YPL101W
Gene name ELP4
Aliases HAP1, KTI9, TOT7
Feature type ORF, Verified
Coordinates Chr XVI:360209..361579
Primary SGDID S000006022


Description of YPL101W: Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity[1][2][3][4]




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References

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  1. Esberg A, et al. (2006) Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis. Mol Cell 24(1):139-48 SGD PMID 17018299
  2. Frohloff F, et al. (2003) Subunit communications crucial for the functional integrity of the yeast RNA polymerase II elongator (gamma-toxin target (TOT)) complex. J Biol Chem 278(2):956-61 SGD PMID 12424236
  3. Glatt S, et al. (2012) The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase.LID - 10.1038/nsmb.2234 [doi] Nat Struct Mol Biol () SGD PMID 22343726
  4. Winkler GS, et al. (2002) Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo. Proc Natl Acad Sci U S A 99(6):3517-22 SGD PMID 11904415

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