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Systematic name YPL101W
Gene name ELP4
Aliases HAP1, KTI9, TOT7
Feature type ORF, Verified
Coordinates Chr XVI:360209..361579
Primary SGDID S000006022

Description of YPL101W: Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity[1][2][3][4]


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  1. Esberg A, et al. (2006) Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis. Mol Cell 24(1):139-48 SGD PMID 17018299
  2. Frohloff F, et al. (2003) Subunit communications crucial for the functional integrity of the yeast RNA polymerase II elongator (gamma-toxin target (TOT)) complex. J Biol Chem 278(2):956-61 SGD PMID 12424236
  3. Glatt S, et al. (2012) The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase.LID - 10.1038/nsmb.2234 [doi] Nat Struct Mol Biol () SGD PMID 22343726
  4. Winkler GS, et al. (2002) Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo. Proc Natl Acad Sci U S A 99(6):3517-22 SGD PMID 11904415

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