Difference between revisions of "YGR116W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003348 YGR116W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003348 YGR116W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SPT6 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SPT6 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:720413..724768
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|nowrap| Chr VII:720409..724764
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003348
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003348
 
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'''Description of YGR116W:''' Transcription elongation factor required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region<ref name='S000073875'>Kaplan CD, et al. (2003) Transcription elongation factors repress transcription initiation from cryptic sites. Science 301(5636):1096-9 {{SGDpaper|S000073875}} PMID 12934008</ref><ref name='S000044170'>Hartzog GA, et al. (1998) Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae. Genes Dev 12(3):357-69 {{SGDpaper|S000044170}} PMID 9450930</ref><ref name='S000041314'>Bortvin A and Winston F (1996) Evidence that Spt6p controls chromatin structure by a direct interaction with histones. Science 272(5267):1473-6
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'''Description of YGR116W:''' Nucleosome remodeling protein; functions in various aspects of transcription, chromatin maintenance, and RNA processing; required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region<ref name='S000041314'>Bortvin A and Winston F (1996) Evidence that Spt6p controls chromatin structure by a direct interaction with histones. Science 272(5267):1473-6 {{SGDpaper|S000041314}} PMID 8633238</ref><ref name='S000144800'>Close D, et al. (2011) Crystal Structures of the S. cerevisiae Spt6 Core and C-Terminal Tandem SH2 Domain. J Mol Biol 408(4):697-713 {{SGDpaper|S000144800}} PMID 21419780</ref><ref name='S000044170'>Hartzog GA, et al. (1998) Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae. Genes Dev 12(3):357-69 {{SGDpaper|S000044170}} PMID 9450930</ref><ref name='S000073875'>Kaplan CD, et al. (2003) Transcription elongation factors repress transcription initiation from cryptic sites. Science 301(5636):1096-9
  {{SGDpaper|S000041314}} PMID 8633238</ref>
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  {{SGDpaper|S000073875}} PMID 12934008</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YGR116W
Gene name SPT6
Aliases CRE2, SSN20
Feature type ORF, Verified
Coordinates Chr VII:720409..724764
Primary SGDID S000003348


Description of YGR116W: Nucleosome remodeling protein; functions in various aspects of transcription, chromatin maintenance, and RNA processing; required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region[1][2][3][4]




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References

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  1. Bortvin A and Winston F (1996) Evidence that Spt6p controls chromatin structure by a direct interaction with histones. Science 272(5267):1473-6 SGD PMID 8633238
  2. Close D, et al. (2011) Crystal Structures of the S. cerevisiae Spt6 Core and C-Terminal Tandem SH2 Domain. J Mol Biol 408(4):697-713 SGD PMID 21419780
  3. Hartzog GA, et al. (1998) Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae. Genes Dev 12(3):357-69 SGD PMID 9450930
  4. Kaplan CD, et al. (2003) Transcription elongation factors repress transcription initiation from cryptic sites. Science 301(5636):1096-9 SGD PMID 12934008

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