YGR116W
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| Systematic name | YGR116W |
| Gene name | SPT6 |
| Aliases | CRE2, SSN20 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:720409..724764 |
| Primary SGDID | S000003348 |
Description of YGR116W: Nucleosome remodeling protein; functions in various aspects of transcription, chromatin maintenance, and RNA processing; required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region[1][2][3][4]
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References
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- ↑ Bortvin A and Winston F (1996) Evidence that Spt6p controls chromatin structure by a direct interaction with histones. Science 272(5267):1473-6 SGD PMID 8633238
- ↑ Close D, et al. (2011) Crystal Structures of the S. cerevisiae Spt6 Core and C-Terminal Tandem SH2 Domain. J Mol Biol 408(4):697-713 SGD PMID 21419780
- ↑ Hartzog GA, et al. (1998) Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae. Genes Dev 12(3):357-69 SGD PMID 9450930
- ↑ Kaplan CD, et al. (2003) Transcription elongation factors repress transcription initiation from cryptic sites. Science 301(5636):1096-9 SGD PMID 12934008
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