Difference between revisions of "YER007W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000809 YER007W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PAC2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PAC2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr V:164526..166082 | |nowrap| Chr V:164526..166082 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000809 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YER007W:''' Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl<ref name='S000058454'>Feierbach B, et al. (1999) Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin. J Cell Biol 144(1):113-24 {{SGDpaper|S000058454}} PMID 9885248</ref><ref name='S000045032'>Hoyt MA, et al. (1997) Saccharomyces cerevisiae PAC2 functions with CIN1, 2 and 4 in a pathway leading to normal microtubule stability. Genetics 146(3):849-57 {{SGDpaper|S000045032}} PMID 9215891</ref><ref name='S000041301'>Vega LR, et al. (1998) An alpha-tubulin mutant destabilizes the heterodimer: phenotypic consequences and interactions with tubulin-binding proteins. Mol Biol Cell 9(9):2349-60 {{SGDpaper|S000041301}} PMID 9725898</ref><ref name='S000039373'>Fleming JA, et al. (2000) Function of tubulin binding proteins in vivo. Genetics 156(1):69-80 |
{{SGDpaper|S000039373}} PMID 10978276</ref> | {{SGDpaper|S000039373}} PMID 10978276</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:45, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YER007W |
| Gene name | PAC2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:164526..166082 |
| Primary SGDID | S000000809 |
Description of YER007W: Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl[1][2][3][4]
</protect>
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References
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- ↑ Feierbach B, et al. (1999) Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin. J Cell Biol 144(1):113-24 SGD PMID 9885248
- ↑ Hoyt MA, et al. (1997) Saccharomyces cerevisiae PAC2 functions with CIN1, 2 and 4 in a pathway leading to normal microtubule stability. Genetics 146(3):849-57 SGD PMID 9215891
- ↑ Vega LR, et al. (1998) An alpha-tubulin mutant destabilizes the heterodimer: phenotypic consequences and interactions with tubulin-binding proteins. Mol Biol Cell 9(9):2349-60 SGD PMID 9725898
- ↑ Fleming JA, et al. (2000) Function of tubulin binding proteins in vivo. Genetics 156(1):69-80 SGD PMID 10978276
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