YER007W
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| Systematic name | YER007W |
| Gene name | PAC2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:164527..166083 |
| Primary SGDID | S000000809 |
Description of YER007W: Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl[1][2][3][4]
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References
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- ↑ Feierbach B, et al. (1999) Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin. J Cell Biol 144(1):113-24 SGD PMID 9885248
- ↑ Fleming JA, et al. (2000) Function of tubulin binding proteins in vivo. Genetics 156(1):69-80 SGD PMID 10978276
- ↑ Hoyt MA, et al. (1997) Saccharomyces cerevisiae PAC2 functions with CIN1, 2 and 4 in a pathway leading to normal microtubule stability. Genetics 146(3):849-57 SGD PMID 9215891
- ↑ Vega LR, et al. (1998) An alpha-tubulin mutant destabilizes the heterodimer: phenotypic consequences and interactions with tubulin-binding proteins. Mol Biol Cell 9(9):2349-60 SGD PMID 9725898
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