Difference between revisions of "YCR084C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000680 YCR084C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TUP1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TUP1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr III:262449..260308 | |nowrap| Chr III:262449..260308 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000680 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YCR084C:''' General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes<ref name='S000062263'>Conlan RS, et al. (1999) The Tup1-Cyc8 protein complex can shift from a transcriptional co-repressor to a transcriptional co-activator. J Biol Chem 274(1):205-10 {{SGDpaper|S000062263}} PMID 9867831</ref><ref name='S000055359'>Keleher CA, et al. (1992) Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68(4):709-19 {{SGDpaper|S000055359}} PMID 1739976</ref><ref name='S000054896'>Zhang L and Guarente L (1994) Evidence that TUP1/SSN6 has a positive effect on the activity of the yeast activator HAP1. Genetics 136(3):813-7 {{SGDpaper|S000054896}} PMID 8005436</ref><ref name='S000054654'>Williams FE, et al. (1991) The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex. Mol Cell Biol 11(6):3307-16 {{SGDpaper|S000054654}} PMID 2038333</ref><ref name='S000054259'>Cooper JP, et al. (1994) The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure. Genes Dev 8(12):1400-10 {{SGDpaper|S000054259}} PMID 7926740</ref><ref name='S000039585'>Edmondson DG, et al. (1996) Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4. Genes Dev 10(10):1247-59 |
{{SGDpaper|S000039585}} PMID 8675011</ref> | {{SGDpaper|S000039585}} PMID 8675011</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Revision as of 07:45, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YCR084C |
| Gene name | TUP1 |
| Aliases | AAR1, AER2, AMM1, CRT4, CYC9, FLK1, ROX4, SFL2, UMR7 |
| Feature type | ORF, Verified |
| Coordinates | Chr III:262449..260308 |
| Primary SGDID | S000000680 |
Description of YCR084C: General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes[1][2][3][4][5][6]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [7] [8]
Interactions
Other Interactions
Other Topic: functional dependence
Other Interactions interaction with Nrg1
Repression by LexA-Nrg1 of a heterologous promoter containing lexA binding sites depends on Tup1. [9] [10]
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References
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- ↑ Conlan RS, et al. (1999) The Tup1-Cyc8 protein complex can shift from a transcriptional co-repressor to a transcriptional co-activator. J Biol Chem 274(1):205-10 SGD PMID 9867831
- ↑ Keleher CA, et al. (1992) Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68(4):709-19 SGD PMID 1739976
- ↑ Zhang L and Guarente L (1994) Evidence that TUP1/SSN6 has a positive effect on the activity of the yeast activator HAP1. Genetics 136(3):813-7 SGD PMID 8005436
- ↑ Williams FE, et al. (1991) The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex. Mol Cell Biol 11(6):3307-16 SGD PMID 2038333
- ↑ Cooper JP, et al. (1994) The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure. Genes Dev 8(12):1400-10 SGD PMID 7926740
- ↑ Edmondson DG, et al. (1996) Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4. Genes Dev 10(10):1247-59 SGD PMID 8675011
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
- ↑ Park SH, et al. (1999) Nrg1 is a transcriptional repressor for glucose repression of STA1 gene expression in Saccharomyces cerevisiae. Mol Cell Biol 19(3):2044-50 SGD PMID 10022891
- ↑ submitted by Valmik K. Vyas on 2003-02-12
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