Difference between revisions of "YOR335C"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 12:02, 21 February 2007

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Systematic name YOR335C
Gene name ALA1
Aliases CDC64
Feature type ORF, Verified
Coordinates Chr XV:949106..946230


Description of YOR335C: Cytoplasmic alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog[1][2]




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References

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  1. Ripmaster TL, et al. (1995) Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen. Proc Natl Acad Sci U S A 92(11):4932-6 SGD PMID 7761427
  2. Wrobel C, et al. (1999) CDC64 encodes cytoplasmic alanyl-tRNA synthetase, Ala1p, of Saccharomyces cerevisiae. J Bacteriol 181(24):7618-20 SGD PMID 10601222

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