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Systematic name YOR335C
Gene name ALA1
Aliases CDC64
Feature type ORF, Verified
Coordinates Chr XV:949109..946233
Primary SGDID S000005862

Description of YOR335C: Cytoplasmic and mitochondrial alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog[1][2][3]


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  1. Ripmaster TL, et al. (1995) Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen. Proc Natl Acad Sci U S A 92(11):4932-6 SGD PMID 7761427
  2. Tang HL, et al. (2004) Translation of a yeast mitochondrial tRNA synthetase initiated at redundant non-AUG codons. J Biol Chem 279(48):49656-63 SGD PMID 15358761
  3. Wrobel C, et al. (1999) CDC64 encodes cytoplasmic alanyl-tRNA synthetase, Ala1p, of Saccharomyces cerevisiae. J Bacteriol 181(24):7618-20 SGD PMID 10601222

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