Difference between revisions of "Chromosome VII History"

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=Sequence Changes=
 
=Sequence Changes=
  
{| border="1" style="border-collapse:collapse; width:90%" cellpadding="4"
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{| border="1" style="border-collapse:collapse; width:90%" cellpadding="6"
 
! Date  !! Affected Features !! Start Coordinate of Change !! End Coordinate of Change !! Type of Change !! Old Sequence !! New Sequence
 
! Date  !! Affected Features !! Start Coordinate of Change !! End Coordinate of Change !! Type of Change !! Old Sequence !! New Sequence
 
|- style="height:30px; width:30px; text-align:center;"
 
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03|| YGR067C|| 622408|| 622408|| Substitution|| A|| T
+
| 2011-02-03
 +
| YGR067C
 +
| 622408
 +
| 622408
 +
| Substitution
 +
| A
 +
| T
 
|-
 
|-
 
| || colspan="6" | A single nucleotide substitution was made in the stop codon of ORF YGR067C, destroying it and increasing the length of the annotated protein by 10 amino acids.
 
| || colspan="6" | A single nucleotide substitution was made in the stop codon of ORF YGR067C, destroying it and increasing the length of the annotated protein by 10 amino acids.
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                 ||||||||||||||||||||||||||||||||||||  ||||||||||||||||||||||
 
                 ||||||||||||||||||||||||||||||||||||  ||||||||||||||||||||||
 
Old    125873  ATATACGATATTAACTCCGGAAAGTGGTCACGAGTCCGTACCGCCTGCCCTGACTGCGAT  125932</pre>
 
Old    125873  ATATACGATATTAACTCCGGAAAGTGGTCACGAGTCCGTACCGCCTGCCCTGACTGCGAT  125932</pre>
 +
Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
 +
 +
|- style="height:30px; width:30px; text-align:center;"
 +
| 2011-02-03
 +
| YGL041C, YGL041W-A
 +
| 419056
 +
| 419056
 +
| Deletion
 +
| G
 +
|
 +
|-
 +
| || colspan="6" | A single nucleotide was deleted within the coding regions of overlapping ORFs YGL041W-A and YGL041C, resulting in altered protein sequences for both ORFs. The YGL041W-A C-terminus and majority of the reading frame remain the same, but the N-terminus has changed and the annotated protein is now 72 amino acids longer. The YGL041C N-terminus remains the same, but the C-terminus has changed and the annotated protein is truncated by one-third of its length (reduced from 104 amino acids to 67 amino acids).
 +
<pre>New    419013  ACTCATGGATCAAATAAATTCGAGGCCTAATGTTCTGG-AAAAGTTAGAAAAGGTTAGCA  419071
 +
                |||||||||||||||||||||||||||||||||||||| |||||||||||||||||||||
 +
Old    419018  ACTCATGGATCAAATAAATTCGAGGCCTAATGTTCTGGGAAAAGTTAGAAAAGGTTAGCA  419077</pre>
 
Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98
 
Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98

Revision as of 10:07, 27 September 2019

This page lists all sequence and annotation changes that have been made to the Chromosome VII systematic reference sequence since its intial release on 1996-07-31. The sequence of Chromosome VII has been updated 125 times, affecting 87 features. The annotation of Chromosome VII has been updated 54 times, affecting 88 features.

Sequence Changes

Date Affected Features Start Coordinate of Change End Coordinate of Change Type of Change Old Sequence New Sequence
2011-02-03 YGR067C 622408 622408 Substitution A T
A single nucleotide substitution was made in the stop codon of ORF YGR067C, destroying it and increasing the length of the annotated protein by 10 amino acids.
New    622362   TCTTTGGCCATTATTTTATTTGGCTAAAAATTTCAATGTTTTTACTTTGTTTATTGTCAG  622421
                |||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old    622366   TCTTTGGCCATTATTTTATTTGGCTAAAAATTTCAATGTTTTAACTTTGTTTATTGTCAG  622425

Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98

2011-02-03 YGL197W 125909 125910 Substitution CG GC
125487 125487 Insertion A
125495 125495 Deletion A
Nucleotide changes within the coding region of MDS3/YGL197W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 262-264 are now QSE rather than HPK, and residue 403 is now Alanine rather than Arginine.
New    125449   TAGACATCTATAACATCTCACAGAATTGCTGGCAATCCGAAA-CCATACCCAAACAACCG  125507
                |||||||||||||||||||||||||||||||||| ||||||| |||||||||||||||||
Old    125454   TAGACATCTATAACATCTCACAGAATTGCTGGCA-TCCGAAAACCATACCCAAACAACCG  125512

New    125868   ATATACGATATTAACTCCGGAAAGTGGTCACGAGTCGCTACCGCCTGCCCTGACTGCGAT  125927
                ||||||||||||||||||||||||||||||||||||  ||||||||||||||||||||||
Old    125873   ATATACGATATTAACTCCGGAAAGTGGTCACGAGTCCGTACCGCCTGCCCTGACTGCGAT  125932

Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98

2011-02-03 YGL041C, YGL041W-A 419056 419056 Deletion G
A single nucleotide was deleted within the coding regions of overlapping ORFs YGL041W-A and YGL041C, resulting in altered protein sequences for both ORFs. The YGL041W-A C-terminus and majority of the reading frame remain the same, but the N-terminus has changed and the annotated protein is now 72 amino acids longer. The YGL041C N-terminus remains the same, but the C-terminus has changed and the annotated protein is truncated by one-third of its length (reduced from 104 amino acids to 67 amino acids).
New    419013   ACTCATGGATCAAATAAATTCGAGGCCTAATGTTCTGG-AAAAGTTAGAAAAGGTTAGCA  419071
                |||||||||||||||||||||||||||||||||||||| |||||||||||||||||||||
Old    419018   ACTCATGGATCAAATAAATTCGAGGCCTAATGTTCTGGGAAAAGTTAGAAAAGGTTAGCA  419077

Engel SR, et al. (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98