Difference between revisions of "YHR082C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YHR082C YHR082C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001124 YHR082C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''KSP1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''KSP1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VIII:271550..268461
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|nowrap| Chr VIII:271548..268459
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001124
 
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'''Description of {{PAGENAME}}:''' Nonessential putative serine/threonine protein kinase of unknown cellular role; overproduction causes allele-specific suppression of the prp20-10 mutation<ref name='S000045656'>Fleischmann M, et al. (1996) Allele-specific suppression of a Saccharomyces cerevisiae prp20 mutation by overexpression of a nuclear serine/threonine protein kinase. Mol Gen Genet 250(5):614-25
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'''Description of YHR082C:''' Ser/thr protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10<ref name='S000126103'>Bharucha N, et al. (2008) Analysis of the Yeast Kinome Reveals a Network of Regulated Protein Localization during Filamentous Growth. Mol Biol Cell 19(7):2708-17 {{SGDpaper|S000126103}} PMID 18417610</ref><ref name='S000045656'>Fleischmann M, et al. (1996) Allele-specific suppression of a Saccharomyces cerevisiae prp20 mutation by overexpression of a nuclear serine/threonine protein kinase. Mol Gen Genet 250(5):614-25 {{SGDpaper|S000045656}} PMID 8676864</ref><ref name='S000147295'>Laxman S and Tu BP (2011) Multiple TORC1-Associated Proteins Regulate Nitrogen Starvation-Dependent Cellular Differentiation in Saccharomyces cerevisiae. PLoS One 6(10):e26081 {{SGDpaper|S000147295}} PMID 22043304</ref><ref name='S000148939'>Umekawa M and Klionsky DJ (2012) The Ksp1 kinase regulates autophagy via the target of rapamycin complex 1 (TORC1) pathway. J Biol Chem ()
  {{SGDpaper|S000045656}} PMID 8676864</ref>
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  {{SGDpaper|S000148939}} PMID 22447937</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 13:05, 4 May 2012

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Systematic name YHR082C
Gene name KSP1
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:271548..268459
Primary SGDID S000001124


Description of YHR082C: Ser/thr protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10[1][2][3][4]




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References

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  1. Bharucha N, et al. (2008) Analysis of the Yeast Kinome Reveals a Network of Regulated Protein Localization during Filamentous Growth. Mol Biol Cell 19(7):2708-17 SGD PMID 18417610
  2. Fleischmann M, et al. (1996) Allele-specific suppression of a Saccharomyces cerevisiae prp20 mutation by overexpression of a nuclear serine/threonine protein kinase. Mol Gen Genet 250(5):614-25 SGD PMID 8676864
  3. Laxman S and Tu BP (2011) Multiple TORC1-Associated Proteins Regulate Nitrogen Starvation-Dependent Cellular Differentiation in Saccharomyces cerevisiae. PLoS One 6(10):e26081 SGD PMID 22043304
  4. Umekawa M and Klionsky DJ (2012) The Ksp1 kinase regulates autophagy via the target of rapamycin complex 1 (TORC1) pathway. J Biol Chem () SGD PMID 22447937

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