YHR082C

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Systematic name YHR082C
Gene name KSP1
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:271548..268459
Primary SGDID S000001124


Description of YHR082C: Ser/thr protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10[1][2][3][4]




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References

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  1. Bharucha N, et al. (2008) Analysis of the Yeast Kinome Reveals a Network of Regulated Protein Localization during Filamentous Growth. Mol Biol Cell 19(7):2708-17 SGD PMID 18417610
  2. Fleischmann M, et al. (1996) Allele-specific suppression of a Saccharomyces cerevisiae prp20 mutation by overexpression of a nuclear serine/threonine protein kinase. Mol Gen Genet 250(5):614-25 SGD PMID 8676864
  3. Laxman S and Tu BP (2011) Multiple TORC1-Associated Proteins Regulate Nitrogen Starvation-Dependent Cellular Differentiation in Saccharomyces cerevisiae. PLoS One 6(10):e26081 SGD PMID 22043304
  4. Umekawa M and Klionsky DJ (2012) The Ksp1 kinase regulates autophagy via the target of rapamycin complex 1 (TORC1) pathway. J Biol Chem () SGD PMID 22447937

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