Difference between revisions of "YLL040C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003963 YLL040C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS13 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS13 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XII: | + | |nowrap| Chr XII:63645..54211 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003963 |
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| − | '''Description of | + | '''Description of YLL040C:''' Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; involved in sporulation, vacuolar protein sorting, prospore membrane formation and protein-Golgi retention; homologous to human CHAC and COH1 which are involved in chorea acanthocytosis and Cohen syndrome, respectively<ref name='S000047092'>Brickner JH and Fuller RS (1997) SOI1 encodes a novel, conserved protein that promotes TGN-endosomal cycling of Kex2p and other membrane proteins by modulating the function of two TGN localization signals. J Cell Biol 139(1):23-36 {{SGDpaper|S000047092}} PMID 9314526</ref><ref name='S000148967'>Park JS and Neiman AM (2012) VPS13 Regulates Membrane Morphogenesis During Sporulation in Saccharomyces cerevisiae. J Cell Sci () {{SGDpaper|S000148967}} PMID 22442115</ref><ref name='S000043240'>Redding K, et al. (1996) Allele-specific suppression of a defective trans-Golgi network (TGN) localization signal in Kex2p identifies three genes involved in localization of TGN transmembrane proteins. Mol Cell Biol 16(11):6208-17 |
{{SGDpaper|S000043240}} PMID 8887651</ref> | {{SGDpaper|S000043240}} PMID 8887651</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
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| + | === Protein Details === | ||
| + | [[Category:Topic:Protein Details]] | ||
| + | ==== Protein Localization ==== | ||
| + | [[Category:Topic:Protein Details:Protein Localization]] | ||
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| + | Vps13p acts in a positive way on TLS1 retrieval from the PVC to the TGN <ref name='S000047092'>Brickner JH and Fuller RS (1997) SOI1 encodes a novel, conserved protein that promotes TGN-endosomal cycling of Kex2p and other membrane proteins by modulating the function of two TGN localization signals. J Cell Biol 139(1):23-36 {{SGDpaper|S000047092}} PMID 9314526</ref> <ref name = 'CAset9538-2003-08-13'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9538 EJ Brace] on 2003-08-13</ref> | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 14:05, 24 April 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YLL040C |
| Gene name | VPS13 |
| Aliases | SOI1, VPT2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:63645..54211 |
| Primary SGDID | S000003963 |
Description of YLL040C: Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; involved in sporulation, vacuolar protein sorting, prospore membrane formation and protein-Golgi retention; homologous to human CHAC and COH1 which are involved in chorea acanthocytosis and Cohen syndrome, respectively[1][2][3]
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Community Commentary
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Protein Details
Protein Localization
Vps13p acts in a positive way on TLS1 retrieval from the PVC to the TGN [1] [4]
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References
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- ↑ Jump up to: 1.0 1.1 Brickner JH and Fuller RS (1997) SOI1 encodes a novel, conserved protein that promotes TGN-endosomal cycling of Kex2p and other membrane proteins by modulating the function of two TGN localization signals. J Cell Biol 139(1):23-36 SGD PMID 9314526
- Jump up ↑ Park JS and Neiman AM (2012) VPS13 Regulates Membrane Morphogenesis During Sporulation in Saccharomyces cerevisiae. J Cell Sci () SGD PMID 22442115
- Jump up ↑ Redding K, et al. (1996) Allele-specific suppression of a defective trans-Golgi network (TGN) localization signal in Kex2p identifies three genes involved in localization of TGN transmembrane proteins. Mol Cell Biol 16(11):6208-17 SGD PMID 8887651
- Jump up ↑ submitted by EJ Brace on 2003-08-13
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