Difference between revisions of "YML123C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YML123C YML123C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004592 YML123C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PHO84 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PHO84 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''phoT''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIII:25801..24038
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|nowrap| Chr XIII:25800..24037
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004592
 
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'''Description of {{PAGENAME}}:''' High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p<ref name='S000074209'>Jensen LT, et al. (2003) The Saccharomyces cerevisiae high affinity phosphate transporter encoded by PHO84 also functions in manganese homeostasis. J Biol Chem 278(43):42036-40 {{SGDpaper|S000074209}} PMID 12923174</ref><ref name='S000054641'>Bun-Ya M, et al. (1991) The PHO84 gene of Saccharomyces cerevisiae encodes an inorganic phosphate transporter. Mol Cell Biol 11(6):3229-38 {{SGDpaper|S000054641}} PMID 2038328</ref><ref name='S000046579'>Nishimura K, et al. (1999) Transcription of some PHO genes in Saccharomyces cerevisiae is regulated by spt7p. Yeast 15(16):1711-7 {{SGDpaper|S000046579}} PMID 10590460</ref><ref name='S000045510'>Bun-ya M, et al. (1996) Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae. Curr Genet 29(4):344-51
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'''Description of YML123C:''' High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p; cells overexpressing Pho84p accumulate heavy metals but do not develop symptoms of metal toxicity<ref name='S000054641'>Bun-Ya M, et al. (1991) The PHO84 gene of Saccharomyces cerevisiae encodes an inorganic phosphate transporter. Mol Cell Biol 11(6):3229-38 {{SGDpaper|S000054641}} PMID 2038328</ref><ref name='S000045510'>Bun-ya M, et al. (1996) Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae. Curr Genet 29(4):344-51 {{SGDpaper|S000045510}} PMID 8598055</ref><ref name='S000074209'>Jensen LT, et al. (2003) The Saccharomyces cerevisiae high affinity phosphate transporter encoded by PHO84 also functions in manganese homeostasis. J Biol Chem 278(43):42036-40 {{SGDpaper|S000074209}} PMID 12923174</ref><ref name='S000046579'>Nishimura K, et al. (1999) Transcription of some PHO genes in Saccharomyces cerevisiae is regulated by spt7p. Yeast 15(16):1711-7 {{SGDpaper|S000046579}} PMID 10590460</ref><ref name='S000148063'>Ofiteru AM, et al. (2011) Overexpression of the PHO84 gene causes heavy metal accumulation and induces Ire1p-dependent unfolded protein response in Saccharomyces cerevisiae cells. Appl Microbiol Biotechnol ()
  {{SGDpaper|S000045510}} PMID 8598055</ref>
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  {{SGDpaper|S000148063}} PMID 22207212</ref>
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 13:05, 27 January 2012

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Systematic name YML123C
Gene name PHO84
Aliases phoT
Feature type ORF, Verified
Coordinates Chr XIII:25800..24037
Primary SGDID S000004592


Description of YML123C: High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p; cells overexpressing Pho84p accumulate heavy metals but do not develop symptoms of metal toxicity[1][2][3][4][5]




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Community Commentary

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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [6] [7]





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References

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  1. Bun-Ya M, et al. (1991) The PHO84 gene of Saccharomyces cerevisiae encodes an inorganic phosphate transporter. Mol Cell Biol 11(6):3229-38 SGD PMID 2038328
  2. Bun-ya M, et al. (1996) Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae. Curr Genet 29(4):344-51 SGD PMID 8598055
  3. Jensen LT, et al. (2003) The Saccharomyces cerevisiae high affinity phosphate transporter encoded by PHO84 also functions in manganese homeostasis. J Biol Chem 278(43):42036-40 SGD PMID 12923174
  4. Nishimura K, et al. (1999) Transcription of some PHO genes in Saccharomyces cerevisiae is regulated by spt7p. Yeast 15(16):1711-7 SGD PMID 10590460
  5. Ofiteru AM, et al. (2011) Overexpression of the PHO84 gene causes heavy metal accumulation and induces Ire1p-dependent unfolded protein response in Saccharomyces cerevisiae cells. Appl Microbiol Biotechnol () SGD PMID 22207212
  6. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  7. submitted by Viktor Boer on 2003-07-25

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