YML123C
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| Systematic name | YML123C |
| Gene name | PHO84 |
| Aliases | phoT |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:25800..24037 |
| Primary SGDID | S000004592 |
Description of YML123C: High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p; cells overexpressing Pho84p accumulate heavy metals but do not develop symptoms of metal toxicity[1][2][3][4][5]
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Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [6] [7]
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References
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- ↑ Bun-Ya M, et al. (1991) The PHO84 gene of Saccharomyces cerevisiae encodes an inorganic phosphate transporter. Mol Cell Biol 11(6):3229-38 SGD PMID 2038328
- ↑ Bun-ya M, et al. (1996) Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae. Curr Genet 29(4):344-51 SGD PMID 8598055
- ↑ Jensen LT, et al. (2003) The Saccharomyces cerevisiae high affinity phosphate transporter encoded by PHO84 also functions in manganese homeostasis. J Biol Chem 278(43):42036-40 SGD PMID 12923174
- ↑ Nishimura K, et al. (1999) Transcription of some PHO genes in Saccharomyces cerevisiae is regulated by spt7p. Yeast 15(16):1711-7 SGD PMID 10590460
- ↑ Ofiteru AM, et al. (2011) Overexpression of the PHO84 gene causes heavy metal accumulation and induces Ire1p-dependent unfolded protein response in Saccharomyces cerevisiae cells. Appl Microbiol Biotechnol () SGD PMID 22207212
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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