Difference between revisions of "YPR189W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006393 YPR189W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SKI3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SKI3 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:912664..916962 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006393 | ||
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| − | '''Description of | + | '''Description of YPR189W:''' Ski complex component and TPR protein, mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay<ref name='S000058465'>Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 {{SGDpaper|S000058465}} PMID 9482746</ref><ref name='S000045264'>Brown JT, et al. (2000) The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo. RNA 6(3):449-57 {{SGDpaper|S000045264}} PMID 10744028</ref><ref name='S000062073'>Lamb JR, et al. (1995) Tetratrico peptide repeat interactions: to TPR or not to TPR? Trends Biochem Sci 20(7):257-9 {{SGDpaper|S000062073}} PMID 7667876</ref><ref name='S000044399'>Toh-E A, et al. (1978) Chromosomal superkiller mutants of Saccharomyces cerevisiae. J Bacteriol 136(3):1002-7 |
| − | {{SGDpaper| | + | {{SGDpaper|S000044399}} PMID 363683</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPR189W |
| Gene name | SKI3 |
| Aliases | SKI5 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:912664..916962 |
| Primary SGDID | S000006393 |
Description of YPR189W: Ski complex component and TPR protein, mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay[1][2][3][4]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 SGD PMID 9482746
- ↑ Brown JT, et al. (2000) The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo. RNA 6(3):449-57 SGD PMID 10744028
- ↑ Lamb JR, et al. (1995) Tetratrico peptide repeat interactions: to TPR or not to TPR? Trends Biochem Sci 20(7):257-9 SGD PMID 7667876
- ↑ Toh-E A, et al. (1978) Chromosomal superkiller mutants of Saccharomyces cerevisiae. J Bacteriol 136(3):1002-7 SGD PMID 363683
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
