Difference between revisions of "YPL120W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006041 YPL120W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS30 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS30 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:322071..323744 |
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+ | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006041 | ||
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− | '''Description of | + | '''Description of YPL120W:''' Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; Complex I is essential in autophagy and Complex II is required for vacuolar protein sorting; ortholog of the higher eukaryotic gene Beclin 1<ref name='S000117386'>Furuya N, et al. (2005) The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy 1(1):46-52 {{SGDpaper|S000117386}} PMID 16874027</ref><ref name='S000059475'>Kihara A, et al. (2001) Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 152(3):519-30 {{SGDpaper|S000059475}} PMID 11157979</ref><ref name='S000048895'>Seaman MN, et al. (1997) Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products. J Cell Biol 137(1):79-92 {{SGDpaper|S000048895}} PMID 9105038</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 |
− | {{SGDpaper| | + | {{SGDpaper|S000051835}} PMID 8224160</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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+ | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YPL120W |
Gene name | VPS30 |
Aliases | APG6, ATG6, VPT30 |
Feature type | ORF, Verified |
Coordinates | Chr XVI:322071..323744 |
Primary SGDID | S000006041 |
Description of YPL120W: Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; Complex I is essential in autophagy and Complex II is required for vacuolar protein sorting; ortholog of the higher eukaryotic gene Beclin 1[1][2][3][4]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Furuya N, et al. (2005) The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy 1(1):46-52 SGD PMID 16874027
- ↑ Kihara A, et al. (2001) Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 152(3):519-30 SGD PMID 11157979
- ↑ Seaman MN, et al. (1997) Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products. J Cell Biol 137(1):79-92 SGD PMID 9105038
- ↑ Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160
See Help:Categories on how to add the wiki page for this gene to a Category </protect>