Difference between revisions of "YOR011W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YOR011W YOR011W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005537 YOR011W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''AUS1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''AUS1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr XV:349679..353863
 
|nowrap| Chr XV:349679..353863
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005537
 
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'''Description of {{PAGENAME}}:''' Transporter of the ATP-binding cassette family, involved in uptake of sterols and anaerobic growth<ref name='S000071132'>Wilcox LJ, et al. (2002) Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. J Biol Chem 277(36):32466-72
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'''Description of YOR011W:''' Plasma membrane sterol transporter of the ATP-binding cassette family; required, along with Pdr11p, for uptake of exogenous sterols and their incorporation into the plasma membrane; activity is stimulated by phosphatidylserine; sterol uptake is required for anaerobic growth because sterol biosynthesis requires oxygen<ref name='S000058997'>Alimardani P, et al. (2004) SUT1-promoted sterol uptake involves the ABC transporter Aus1 and the mannoprotein Dan1 whose synergistic action is sufficient for this process. Biochem J 381(Pt 1):195-202 {{SGDpaper|S000058997}} PMID 15035656</ref><ref name='S000141175'>Kohut P, et al. (2011) The role of ABC proteins Aus1p and Pdr11p in the uptake of external sterols in yeast: Dehydroergosterol fluorescence study. Biochem Biophys Res Commun 404(1):233-8 {{SGDpaper|S000141175}} PMID 21110944</ref><ref name='S000145204'>Marek M, et al. (2011) The yeast plasma membrane ABC transporter Aus1: Purification, characterization and effect of lipids on its activity. J Biol Chem () {{SGDpaper|S000145204}} PMID 21521689</ref><ref name='S000071132'>Wilcox LJ, et al. (2002) Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. J Biol Chem 277(36):32466-72
 
  {{SGDpaper|S000071132}} PMID 12077145</ref>
 
  {{SGDpaper|S000071132}} PMID 12077145</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YOR011W
Gene name AUS1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:349679..353863
Primary SGDID S000005537


Description of YOR011W: Plasma membrane sterol transporter of the ATP-binding cassette family; required, along with Pdr11p, for uptake of exogenous sterols and their incorporation into the plasma membrane; activity is stimulated by phosphatidylserine; sterol uptake is required for anaerobic growth because sterol biosynthesis requires oxygen[1][2][3][4]




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References

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  1. Alimardani P, et al. (2004) SUT1-promoted sterol uptake involves the ABC transporter Aus1 and the mannoprotein Dan1 whose synergistic action is sufficient for this process. Biochem J 381(Pt 1):195-202 SGD PMID 15035656
  2. Kohut P, et al. (2011) The role of ABC proteins Aus1p and Pdr11p in the uptake of external sterols in yeast: Dehydroergosterol fluorescence study. Biochem Biophys Res Commun 404(1):233-8 SGD PMID 21110944
  3. Marek M, et al. (2011) The yeast plasma membrane ABC transporter Aus1: Purification, characterization and effect of lipids on its activity. J Biol Chem () SGD PMID 21521689
  4. Wilcox LJ, et al. (2002) Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. J Biol Chem 277(36):32466-72 SGD PMID 12077145

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