Difference between revisions of "YNL015W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YNL015W YNL015W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004960 YNL015W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PBI2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PBI2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIV:605385..605612
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|nowrap| Chr XIV:605384..605611
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004960
 
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'''Description of {{PAGENAME}}:''' Cytosolic inhibitor of vacuolar proteinase B, required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion<ref name='S000075883'>Betz H (1975) Levels and turnover of the proteinase B inhibitors in yeast. Biochim Biophys Acta 404(1):142-51 {{SGDpaper|S000075883}} PMID 1100120</ref><ref name='S000074126'>Elazar Z, et al. (2003) Involvement of LMA1 and GATE-16 family members in intracellular membrane dynamics. Biochim Biophys Acta 1641(2-3):145-56 {{SGDpaper|S000074126}} PMID 12914955</ref><ref name='S000064306'>Slusarewicz P, et al. (1997) I2B is a small cytosolic protein that participates in vacuole fusion. Proc Natl Acad Sci U S A 94(11):5582-7 {{SGDpaper|S000064306}} PMID 9159115</ref><ref name='S000048402'>Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306
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'''Description of YNL015W:''' Cytosolic inhibitor of vacuolar proteinase B (PRB1), required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion<ref name='S000075883'>Betz H (1975) Levels and turnover of the proteinase B inhibitors in yeast. Biochim Biophys Acta 404(1):142-51 {{SGDpaper|S000075883}} PMID 1100120</ref><ref name='S000074126'>Elazar Z, et al. (2003) Involvement of LMA1 and GATE-16 family members in intracellular membrane dynamics. Biochim Biophys Acta 1641(2-3):145-56 {{SGDpaper|S000074126}} PMID 12914955</ref><ref name='S000064306'>Slusarewicz P, et al. (1997) I2B is a small cytosolic protein that participates in vacuole fusion. Proc Natl Acad Sci U S A 94(11):5582-7 {{SGDpaper|S000064306}} PMID 9159115</ref><ref name='S000048402'>Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306
 
  {{SGDpaper|S000048402}} PMID 9015301</ref>
 
  {{SGDpaper|S000048402}} PMID 9015301</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YNL015W
Gene name PBI2
Aliases I2B, IB2, LMA1
Feature type ORF, Verified
Coordinates Chr XIV:605384..605611
Primary SGDID S000004960


Description of YNL015W: Cytosolic inhibitor of vacuolar proteinase B (PRB1), required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion[1][2][3][4]




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References

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  1. Betz H (1975) Levels and turnover of the proteinase B inhibitors in yeast. Biochim Biophys Acta 404(1):142-51 SGD PMID 1100120
  2. Elazar Z, et al. (2003) Involvement of LMA1 and GATE-16 family members in intracellular membrane dynamics. Biochim Biophys Acta 1641(2-3):145-56 SGD PMID 12914955
  3. Slusarewicz P, et al. (1997) I2B is a small cytosolic protein that participates in vacuole fusion. Proc Natl Acad Sci U S A 94(11):5582-7 SGD PMID 9159115
  4. Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306 SGD PMID 9015301

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