Difference between revisions of "YLR045C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004035 YLR045C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STU2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STU2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr XII: | + | |nowrap| Chr XII:237703..235037 |
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− | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004035 |
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− | '''Description of | + | '''Description of YLR045C:''' Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p<ref name='S000044510'>Chen XP, et al. (1998) The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly. J Cell Biol 141(5):1169-79 {{SGDpaper|S000044510}} PMID 9606209</ref><ref name='S000068994'>Kosco KA, et al. (2001) Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast. Mol Biol Cell 12(9):2870-80 {{SGDpaper|S000068994}} PMID 11553724</ref><ref name='S000060134'>Severin F, et al. (2001) Stu2 promotes mitotic spindle elongation in anaphase. J Cell Biol 153(2):435-42 {{SGDpaper|S000060134}} PMID 11309422</ref><ref name='S000051489'>Wang PJ and Huffaker TC (1997) Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body. J Cell Biol 139(5):1271-80 |
− | + | {{SGDpaper|S000051489}} PMID 9382872</ref> | |
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==Community Commentary== | ==Community Commentary== | ||
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+ | === Protein Details === | ||
+ | [[Category:Topic:Protein Details]] | ||
+ | ==== Protein Modification ==== | ||
+ | [[Category:Topic:Protein Details:Protein Modification]] | ||
+ | '''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]] | ||
+ | |||
+ | Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. <ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref> <ref name = 'CAset7903-2004-01-29'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=7903 Jeff Ubersax] on 2004-01-29</ref> | ||
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YLR045C |
Gene name | STU2 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XII:237703..235037 |
Primary SGDID | S000004035 |
Description of YLR045C: Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p[1][2][3][4]
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Community Commentary
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
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References
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- ↑ Chen XP, et al. (1998) The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly. J Cell Biol 141(5):1169-79 SGD PMID 9606209
- ↑ Kosco KA, et al. (2001) Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast. Mol Biol Cell 12(9):2870-80 SGD PMID 11553724
- ↑ Severin F, et al. (2001) Stu2 promotes mitotic spindle elongation in anaphase. J Cell Biol 153(2):435-42 SGD PMID 11309422
- ↑ Wang PJ and Huffaker TC (1997) Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body. J Cell Biol 139(5):1271-80 SGD PMID 9382872
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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