Difference between revisions of "YJR119C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003880 YJR119C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''JHD2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''JHD2 '' | ||
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' '' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''KDM5'' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr X: | + | |nowrap| Chr X:646490..644304 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003880 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003880 | ||
|} | |} | ||
<br> | <br> | ||
| − | '''Description of YJR119C:''' JmjC domain family histone demethylase specific for H3-K4 ( | + | '''Description of YJR119C:''' JmjC domain family histone demethylase specific for H3-K4 (histone H3 Lys4); removes methyl groups specifically added by Set1p methyltransferase; protein levels regulated by Not4p (E3 ubiquitin ligase) polyubiquitin-mediated degradation<ref name='S000121024'>Liang G, et al. (2007) Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase. Nat Struct Mol Biol 14(3):243-5 {{SGDpaper|S000121024}} PMID 17310254</ref><ref name='S000129902'>Mersman DP, et al. (2009) Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression. Genes Dev 23(8):951-62 {{SGDpaper|S000129902}} PMID 19346402</ref><ref name='S000121023'>Seward DJ, et al. (2007) Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins. Nat Struct Mol Biol 14(3):240-2 {{SGDpaper|S000121023}} PMID 17310255</ref><ref name='S000121921'>Tu S, et al. (2007) Identification of histone demethylases in Saccharomyces cerevisiae. J Biol Chem 282(19):14262-71 |
| − | {{SGDpaper| | + | {{SGDpaper|S000121921}} PMID 17369256</ref> |
<br> | <br> | ||
<br> | <br> | ||
Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YJR119C |
| Gene name | JHD2 |
| Aliases | KDM5 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:646490..644304 |
| Primary SGDID | S000003880 |
Description of YJR119C: JmjC domain family histone demethylase specific for H3-K4 (histone H3 Lys4); removes methyl groups specifically added by Set1p methyltransferase; protein levels regulated by Not4p (E3 ubiquitin ligase) polyubiquitin-mediated degradation[1][2][3][4]
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References
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- ↑ Liang G, et al. (2007) Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase. Nat Struct Mol Biol 14(3):243-5 SGD PMID 17310254
- ↑ Mersman DP, et al. (2009) Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression. Genes Dev 23(8):951-62 SGD PMID 19346402
- ↑ Seward DJ, et al. (2007) Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins. Nat Struct Mol Biol 14(3):240-2 SGD PMID 17310255
- ↑ Tu S, et al. (2007) Identification of histone demethylases in Saccharomyces cerevisiae. J Biol Chem 282(19):14262-71 SGD PMID 17369256
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