Difference between revisions of "YGR122W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003354 YGR122W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||'' ''
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YGR122W
Gene name
Aliases
Feature type ORF, Verified
Coordinates Chr VII:733935..735143
Primary SGDID S000003354


Description of YGR122W: Probable ortholog of A. nidulans PalC, which is involved in pH regulation and binds to the ESCRT-III complex; null mutant does not properly process Rim101p and has decreased resistance to rapamycin; GFP-fusion protein is cytoplasmic[1][2][3][4]




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References

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  1. Galindo A, et al. (2007) PalC, One of Two Bro1 Domain Proteins in the Fungal pH Signalling Pathway, Localizes to Cortical Structures and Binds Vps32. Traffic 8(10):1346-64 SGD PMID 17696968
  2. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  3. Rothfels K, et al. (2005) Components of the ESCRT pathway, DFG16, and YGR122w are required for Rim101 to act as a corepressor with Nrg1 at the negative regulatory element of the DIT1 gene of Saccharomyces cerevisiae. Mol Cell Biol 25(15):6772-88 SGD PMID 16024810
  4. Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 SGD PMID 15883373

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