YGR122W
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| Systematic name | YGR122W |
| Gene name | |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:733935..735143 |
| Primary SGDID | S000003354 |
Description of YGR122W: Probable ortholog of A. nidulans PalC, which is involved in pH regulation and binds to the ESCRT-III complex; null mutant does not properly process Rim101p and has decreased resistance to rapamycin; GFP-fusion protein is cytoplasmic[1][2][3][4]
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References
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- ↑ Galindo A, et al. (2007) PalC, One of Two Bro1 Domain Proteins in the Fungal pH Signalling Pathway, Localizes to Cortical Structures and Binds Vps32. Traffic 8(10):1346-64 SGD PMID 17696968
- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Rothfels K, et al. (2005) Components of the ESCRT pathway, DFG16, and YGR122w are required for Rim101 to act as a corepressor with Nrg1 at the negative regulatory element of the DIT1 gene of Saccharomyces cerevisiae. Mol Cell Biol 25(15):6772-88 SGD PMID 16024810
- ↑ Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 SGD PMID 15883373
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