Difference between revisions of "YDR108W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002515 YDR108W] |
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||'' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TRS85 '' |
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''MUM1 | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''GSG1, MUM1'' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:671269..673365 |
|- | |- | ||
| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002515 |
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| − | '''Description of | + | '''Description of YDR108W:''' Subunit of TRAPPIII (transport protein particle), a multimeric guanine nucleotide-exchange factor for Ypt1p, required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role<ref name='S000039264'>Engebrecht J, et al. (1998) Yeast meiotic mutants proficient for the induction of ectopic recombination. Genetics 148(2):581-98 {{SGDpaper|S000039264}} PMID 9504908</ref><ref name='S000045171'>Kaytor MD and Livingston DM (1995) GSG1, a yeast gene required for sporulation. Yeast 11(12):1147-55 {{SGDpaper|S000045171}} PMID 8619313</ref><ref name='S000134404'>Lynch-Day MA, et al. (2010) Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci U S A 107(17):7811-6 {{SGDpaper|S000134404}} PMID 20375281</ref><ref name='S000086066'>Meiling-Wesse K, et al. (2005) Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. J Biol Chem 280(39):33669-78 {{SGDpaper|S000086066}} PMID 16079147</ref><ref name='S000117385'>Nazarko TY, et al. (2005) Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae. Autophagy 1(1):37-45 |
| − | {{SGDpaper| | + | {{SGDpaper|S000117385}} PMID 16874038</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR108W |
| Gene name | TRS85 |
| Aliases | GSG1, MUM1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:671269..673365 |
| Primary SGDID | S000002515 |
Description of YDR108W: Subunit of TRAPPIII (transport protein particle), a multimeric guanine nucleotide-exchange factor for Ypt1p, required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role[1][2][3][4][5]
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Contents
Community Commentary
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References
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- ↑ Engebrecht J, et al. (1998) Yeast meiotic mutants proficient for the induction of ectopic recombination. Genetics 148(2):581-98 SGD PMID 9504908
- ↑ Kaytor MD and Livingston DM (1995) GSG1, a yeast gene required for sporulation. Yeast 11(12):1147-55 SGD PMID 8619313
- ↑ Lynch-Day MA, et al. (2010) Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci U S A 107(17):7811-6 SGD PMID 20375281
- ↑ Meiling-Wesse K, et al. (2005) Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. J Biol Chem 280(39):33669-78 SGD PMID 16079147
- ↑ Nazarko TY, et al. (2005) Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae. Autophagy 1(1):37-45 SGD PMID 16874038
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