Difference between revisions of "YDL074C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002232 YDL074C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''BRE1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''BRE1 '' | ||
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|nowrap| Chr IV:326149..324047 | |nowrap| Chr IV:326149..324047 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002232 |
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| − | '''Description of | + | '''Description of YDL074C:''' E3 ubiquitin ligase, forms heterodimer with Rad6p to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control<ref name='S000130696'>Kim J and Roeder RG (2009) Direct Bre1-Paf1 Complex Interactions and RING Finger-independent Bre1-Rad6 Interactions Mediate Histone H2B Ubiquitylation in Yeast. J Biol Chem 284(31):20582-92 {{SGDpaper|S000130696}} PMID 19531475</ref><ref name='S000072783'>Wood A, et al. (2003) Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Mol Cell 11(1):267-74 {{SGDpaper|S000072783}} PMID 12535539</ref><ref name='S000086737'>Wysocki R, et al. (2005) Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. Mol Cell Biol 25(19):8430-43 |
| − | {{SGDpaper| | + | {{SGDpaper|S000086737}} PMID 16166626</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDL074C |
| Gene name | BRE1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:326149..324047 |
| Primary SGDID | S000002232 |
Description of YDL074C: E3 ubiquitin ligase, forms heterodimer with Rad6p to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control[1][2][3]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Kim J and Roeder RG (2009) Direct Bre1-Paf1 Complex Interactions and RING Finger-independent Bre1-Rad6 Interactions Mediate Histone H2B Ubiquitylation in Yeast. J Biol Chem 284(31):20582-92 SGD PMID 19531475
- ↑ Wood A, et al. (2003) Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Mol Cell 11(1):267-74 SGD PMID 12535539
- ↑ Wysocki R, et al. (2005) Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. Mol Cell Biol 25(19):8430-43 SGD PMID 16166626
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