Difference between revisions of "YKR002W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YKR002W YKR002W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001710 YKR002W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PAP1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PAP1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XI:442875..444581
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|nowrap| Chr XI:443232..444938
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001710
 
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'''Description of {{PAGENAME}}:''' Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs<ref name='S000076367'>Kuai L, et al. (2004) Polyadenylation of rRNA in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 101(23):8581-6 {{SGDpaper|S000076367}} PMID 15173578</ref><ref name='S000059583'>Brodsky AS and Silver PA (2000) Pre-mRNA processing factors are required for nuclear export. RNA 6(12):1737-49 {{SGDpaper|S000059583}} PMID 11142374</ref><ref name='S000043351'>Mizrahi N and Moore C (2000) Posttranslational phosphorylation and ubiquitination of the Saccharomyces cerevisiae Poly(A) polymerase at the S/G(2) stage of the cell cycle. Mol Cell Biol 20(8):2794-802 {{SGDpaper|S000043351}} PMID 10733582</ref><ref name='S000040911'>Preker PJ, et al. (1997) A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor. EMBO J 16(15):4727-37
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'''Description of YKR002W:''' Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs; required for gene looping<ref name='S000059583'>Brodsky AS and Silver PA (2000) Pre-mRNA processing factors are required for nuclear export. RNA 6(12):1737-49 {{SGDpaper|S000059583}} PMID 11142374</ref><ref name='S000076367'>Kuai L, et al. (2004) Polyadenylation of rRNA in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 101(23):8581-6 {{SGDpaper|S000076367}} PMID 15173578</ref><ref name='S000146442'>Medler S, et al. (2011) Evidence for a complex of TFIIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping. J Biol Chem () {{SGDpaper|S000146442}} PMID 21835917</ref><ref name='S000043351'>Mizrahi N and Moore C (2000) Posttranslational phosphorylation and ubiquitination of the Saccharomyces cerevisiae Poly(A) polymerase at the S/G(2) stage of the cell cycle. Mol Cell Biol 20(8):2794-802 {{SGDpaper|S000043351}} PMID 10733582</ref><ref name='S000040911'>Preker PJ, et al. (1997) A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor. EMBO J 16(15):4727-37
 
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  {{SGDpaper|S000040911}} PMID 9303317</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YKR002W
Gene name PAP1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:443232..444938
Primary SGDID S000001710


Description of YKR002W: Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs; required for gene looping[1][2][3][4][5]




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References

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  1. Brodsky AS and Silver PA (2000) Pre-mRNA processing factors are required for nuclear export. RNA 6(12):1737-49 SGD PMID 11142374
  2. Kuai L, et al. (2004) Polyadenylation of rRNA in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 101(23):8581-6 SGD PMID 15173578
  3. Medler S, et al. (2011) Evidence for a complex of TFIIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping. J Biol Chem () SGD PMID 21835917
  4. Mizrahi N and Moore C (2000) Posttranslational phosphorylation and ubiquitination of the Saccharomyces cerevisiae Poly(A) polymerase at the S/G(2) stage of the cell cycle. Mol Cell Biol 20(8):2794-802 SGD PMID 10733582
  5. Preker PJ, et al. (1997) A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor. EMBO J 16(15):4727-37 SGD PMID 9303317

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