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Systematic name YKR002W
Gene name PAP1
Feature type ORF, Verified
Coordinates Chr XI:443232..444938
Primary SGDID S000001710

Description of YKR002W: Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs; required for gene looping[1][2][3][4][5]


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  1. Brodsky AS and Silver PA (2000) Pre-mRNA processing factors are required for nuclear export. RNA 6(12):1737-49 SGD PMID 11142374
  2. Kuai L, et al. (2004) Polyadenylation of rRNA in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 101(23):8581-6 SGD PMID 15173578
  3. Medler S, et al. (2011) Evidence for a complex of TFIIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping. J Biol Chem () SGD PMID 21835917
  4. Mizrahi N and Moore C (2000) Posttranslational phosphorylation and ubiquitination of the Saccharomyces cerevisiae Poly(A) polymerase at the S/G(2) stage of the cell cycle. Mol Cell Biol 20(8):2794-802 SGD PMID 10733582
  5. Preker PJ, et al. (1997) A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor. EMBO J 16(15):4727-37 SGD PMID 9303317

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