Difference between revisions of "YIR011C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001450 YIR011C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001450 YIR011C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''STS1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''STS1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IX:378243..377284
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|nowrap| Chr IX:378246..377287
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001450
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001450
 
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'''Description of YIR011C:''' Protein that interacts with the karyopherin Srp1p; may have a role with Srp1p in ubiquitin-mediated protein degradation<ref name='S000054650'>Amrani N, et al. (1996) Mutations in STS1 suppress the defect in 3' mRNA processing caused by the rna15-2 mutation in Saccharomyces cerevisiae. Mol Gen Genet 252(5):552-62 {{SGDpaper|S000054650}} PMID 8914516</ref><ref name='S000045318'>Tabb MM, et al. (2000) Evidence for separable functions of Srp1p, the yeast homolog of importin alpha (Karyopherin alpha): role for Srp1p and Sts1p in protein degradation. Mol Cell Biol 20(16):6062-73
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'''Description of YIR011C:''' Protein required for localizing proteasomes to the nucleus; interacts with the karyopherin Srp1p; involved in ubiquitin-mediated protein degradation<ref name='S000054650'>Amrani N, et al. (1996) Mutations in STS1 suppress the defect in 3' mRNA processing caused by the rna15-2 mutation in Saccharomyces cerevisiae. Mol Gen Genet 252(5):552-62 {{SGDpaper|S000054650}} PMID 8914516</ref><ref name='S000144538'>Chen L, et al. (2011) Sts1 plays a key role in targeting proteasomes to the nucleus. J Biol Chem 286(4):3104-18 {{SGDpaper|S000144538}} PMID 21075847</ref><ref name='S000045318'>Tabb MM, et al. (2000) Evidence for separable functions of Srp1p, the yeast homolog of importin alpha (Karyopherin alpha): role for Srp1p and Sts1p in protein degradation. Mol Cell Biol 20(16):6062-73
 
  {{SGDpaper|S000045318}} PMID 10913188</ref>
 
  {{SGDpaper|S000045318}} PMID 10913188</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YIR011C
Gene name STS1
Aliases DBF8, SSM5
Feature type ORF, Verified
Coordinates Chr IX:378246..377287
Primary SGDID S000001450


Description of YIR011C: Protein required for localizing proteasomes to the nucleus; interacts with the karyopherin Srp1p; involved in ubiquitin-mediated protein degradation[1][2][3]




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References

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  1. Amrani N, et al. (1996) Mutations in STS1 suppress the defect in 3' mRNA processing caused by the rna15-2 mutation in Saccharomyces cerevisiae. Mol Gen Genet 252(5):552-62 SGD PMID 8914516
  2. Chen L, et al. (2011) Sts1 plays a key role in targeting proteasomes to the nucleus. J Biol Chem 286(4):3104-18 SGD PMID 21075847
  3. Tabb MM, et al. (2000) Evidence for separable functions of Srp1p, the yeast homolog of importin alpha (Karyopherin alpha): role for Srp1p and Sts1p in protein degradation. Mol Cell Biol 20(16):6062-73 SGD PMID 10913188

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