Difference between revisions of "YER172C"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
(10 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN--> | <!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN--> | ||
{{PageTop}} | {{PageTop}} | ||
+ | <protect> | ||
{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
|- | |- | ||
− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000974 YER172C] |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''BRR2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''BRR2 '' | ||
Line 12: | Line 13: | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr V: | + | |nowrap| Chr V:536021..529530 |
|- | |- | ||
− | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000974 |
|} | |} | ||
<br> | <br> | ||
− | '''Description of | + | '''Description of YER172C:''' RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD<ref name='S000053606'>Lauber J, et al. (1996) The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases. EMBO J 15(15):4001-15 {{SGDpaper|S000053606}} PMID 8670905</ref><ref name='S000044662'>Noble SM and Guthrie C (1996) Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations. Genetics 143(1):67-80 {{SGDpaper|S000044662}} PMID 8722763</ref><ref name='S000061922'>Raghunathan PL and Guthrie C (1998) RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2. Curr Biol 8(15):847-55 {{SGDpaper|S000061922}} PMID 9705931</ref><ref name='S000056328'>Xu D, et al. (1996) An RNA-dependent ATPase associated with U2/U6 snRNAs in pre-mRNA splicing. Nature 381(6584):709-13 |
− | + | {{SGDpaper|S000056328}} PMID 8649518</ref> | |
<br> | <br> | ||
<br> | <br> | ||
<br> | <br> | ||
<br> | <br> | ||
− | + | <br> | |
− | + | </protect> | |
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
Line 42: | Line 37: | ||
{{ShortCenteredHR}} | {{ShortCenteredHR}} | ||
+ | |||
+ | |||
+ | |||
+ | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
+ | <!-- | ||
+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
+ | --> | ||
+ | |||
+ | |||
+ | |||
+ | <protect> | ||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} | ||
+ | </protect> |
Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YER172C |
Gene name | BRR2 |
Aliases | PRP44, RSS1, SLT22, SNU246 |
Feature type | ORF, Verified |
Coordinates | Chr V:536021..529530 |
Primary SGDID | S000000974 |
Description of YER172C: RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD[1][2][3][4]
</protect>
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Two Hybrid
Two Hybrid interaction with Prp8
C-terminus of Prp8 binds to full length Brr2. N-terminus of Prp8 binds to Prp39 [5] [6]
<protect>
References
See Help:References on how to add references
- ↑ Lauber J, et al. (1996) The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases. EMBO J 15(15):4001-15 SGD PMID 8670905
- ↑ Noble SM and Guthrie C (1996) Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations. Genetics 143(1):67-80 SGD PMID 8722763
- ↑ Raghunathan PL and Guthrie C (1998) RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2. Curr Biol 8(15):847-55 SGD PMID 9705931
- ↑ Xu D, et al. (1996) An RNA-dependent ATPase associated with U2/U6 snRNAs in pre-mRNA splicing. Nature 381(6584):709-13 SGD PMID 8649518
- ↑ van Nues RW and Beggs JD (2001) Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics 157(4):1451-67 SGD PMID 11290703
- ↑ submitted by Richard Grainger on 2003-04-11
See Help:Categories on how to add the wiki page for this gene to a Category </protect>