Difference between revisions of "YEL019C"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
(Automated import of articles)
 
(8 intermediate revisions by the same user not shown)
Line 4: Line 4:
 
{|{{Prettytable}} align = 'right' width = '200px'
 
{|{{Prettytable}} align = 'right' width = '200px'
 
|-
 
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YEL019C YEL019C]  
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000745 YEL019C]  
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MMS21 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MMS21 ''
 
|-
 
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''NSE2, PSO10''
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
Line 14: Line 14:
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr V:121301..120498
 
|nowrap| Chr V:121301..120498
 +
|-
 +
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000745
 
|}
 
|}
 
<br>
 
<br>
'''Description of {{PAGENAME}}:''' SUMO ligase involved in chromosomal organization and DNA repair; essential subunit of the Mms21-Smc5-Smc6 complex; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination<ref name='S000080949'>Zhao X and Blobel G (2005) A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A 102(13):4777-82 {{SGDpaper|S000080949}} PMID 15738391</ref><ref name='S000049039'>Montelone BA and Koelliker KJ (1995) Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast. Curr Genet 27(2):102-9 {{SGDpaper|S000049039}} PMID 7788712</ref><ref name='S000047995'>Prakash S and Prakash L (1977) Increased spontaneous mitotic segregation in MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 87(2):229-36
+
'''Description of YEL019C:''' SUMO ligase and component of the SMC5-SMC6 complex; this complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination<ref name='S000142482'>Bermudez-Lopez M, et al. (2010) The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages. Nucleic Acids Res 38(19):6502-12 {{SGDpaper|S000142482}} PMID 20571088</ref><ref name='S000049039'>Montelone BA and Koelliker KJ (1995) Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast. Curr Genet 27(2):102-9 {{SGDpaper|S000049039}} PMID 7788712</ref><ref name='S000047995'>Prakash S and Prakash L (1977) Increased spontaneous mitotic segregation in MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 87(2):229-36 {{SGDpaper|S000047995}} PMID 200524</ref><ref name='S000080949'>Zhao X and Blobel G (2005) A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A 102(13):4777-82
  {{SGDpaper|S000047995}} PMID 200524</ref>
+
  {{SGDpaper|S000080949}} PMID 15738391</ref>
 
<br>
 
<br>
 
<br>
 
<br>
Line 37: Line 39:
 
J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
-->
 
-->
 +
 +
  
 
<protect>
 
<protect>

Latest revision as of 06:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YEL019C
Gene name MMS21
Aliases NSE2, PSO10
Feature type ORF, Verified
Coordinates Chr V:121301..120498
Primary SGDID S000000745


Description of YEL019C: SUMO ligase and component of the SMC5-SMC6 complex; this complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination[1][2][3][4]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Bermudez-Lopez M, et al. (2010) The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages. Nucleic Acids Res 38(19):6502-12 SGD PMID 20571088
  2. Montelone BA and Koelliker KJ (1995) Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast. Curr Genet 27(2):102-9 SGD PMID 7788712
  3. Prakash S and Prakash L (1977) Increased spontaneous mitotic segregation in MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 87(2):229-36 SGD PMID 200524
  4. Zhao X and Blobel G (2005) A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A 102(13):4777-82 SGD PMID 15738391

See Help:Categories on how to add the wiki page for this gene to a Category </protect>