Difference between revisions of "YBR066C"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
| (8 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN--> | <!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN--> | ||
{{PageTop}} | {{PageTop}} | ||
| + | <protect> | ||
{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
|- | |- | ||
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000270 YBR066C] |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NRG2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NRG2 '' | ||
| Line 12: | Line 13: | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr II: | + | |nowrap| Chr II:370699..370037 |
|- | |- | ||
| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000270 |
|} | |} | ||
<br> | <br> | ||
| − | '''Description of | + | '''Description of YBR066C:''' Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p<ref name='S000070028'>Kuchin S, et al. (2002) Snf1 protein kinase and the repressors Nrg1 and Nrg2 regulate FLO11, haploid invasive growth, and diploid pseudohyphal differentiation. Mol Cell Biol 22(12):3994-4000 {{SGDpaper|S000070028}} PMID 12024013</ref><ref name='S000060795'>Vyas VK, et al. (2001) Interaction of the repressors Nrg1 and Nrg2 with the Snf1 protein kinase in Saccharomyces cerevisiae. Genetics 158(2):563-72 |
{{SGDpaper|S000060795}} PMID 11404322</ref> | {{SGDpaper|S000060795}} PMID 11404322</ref> | ||
<br> | <br> | ||
| Line 23: | Line 24: | ||
<br> | <br> | ||
<br> | <br> | ||
| + | <br> | ||
| + | </protect> | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
| Line 110: | Line 113: | ||
{{ShortCenteredHR}} | {{ShortCenteredHR}} | ||
| + | |||
| + | |||
| + | |||
| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
| + | <!-- | ||
| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
| + | --> | ||
| + | |||
| + | |||
| + | |||
| + | <protect> | ||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} | ||
| + | </protect> | ||
Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBR066C |
| Gene name | NRG2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:370699..370037 |
| Primary SGDID | S000000270 |
Description of YBR066C: Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p[1][2]
</protect>
Contents
[hide]Community Commentary
About Community Commentary. Please share your knowledge!
Alleles, Strains, and Phenotypes
Multiple Knockout Strains
Strain Background: Sigma1278b (Sigma 2000 series)
Genotype: MCY4708
Together with: NRG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null)
Deletion of nrg2 partially suppresses gal83's defect in invasive growth, plastic adherance, and STA2-lacZ expression. [3] [4]
Strain Background: Sigma1278b (Sigma 2000 series)
Genotype: MCY4712
Together with: NRG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null)
Deletion of nrg1 and nrg2 suppresses gal83's defect in invasive growth, plastic adherance, and STA2-lacZ expression, better than deletion of either nrg alone. [3] [4]
Strain Background: Sigma1278b (Sigma 2000 series)
Genotype: MCY4708
Together with: NRG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null)
Deletion of nrg2 partially suppresses gal83's defect in invasive growth, plastic adherance, and STA2-lacZ expression. [3] [4]
Strain Background: Sigma1278b (Sigma 2000 series)
Genotype: MCY4712
Together with: NRG1, SIP1, GAL83, SIP2
Phenotype(s): Loss of function (Null)
Deletion of nrg1 and nrg2 suppresses gal83's defect in invasive growth, plastic adherance, and STA2-lacZ expression, better than deletion of either nrg alone. [3] [4]
Overexpression
Phenotype(s): Dominant, Gain of function
Overexpression of VP16-Nrg2 results in partial derepression of SUC2 in glucose grown cells. [2] [5]
Interactions
Genetic
YBR066C is a suppressor of Snf1
Strain Background: Sigma 1278b
Mutation type(s): complete deletion, complete deletion
Deletion of Nrg2 partially suppresses Snf1's defect in invasive growth, biofilm formation, FLO11 expression, and STA2 expression. [1] [5]
Physical
Physical interaction with Snf1
LexA-Snf1 coimmunoprecipitates HA3-Nrg2 [2] [5]
Physical interaction with Snf1
Snf1 coimmunoprecipitates with HA3-Nrg2 [2] [5]
Two Hybrid
Two Hybrid interaction with Snf1
Snf1 kinase domain interacts with Nrg2 [2] [5]
Protein Details
Protein Function/Process
LexA-Nrg2 represses transcription from a heterologous promoter containing LexA binding sites. [2] [5]
<protect>
References
See Help:References on how to add references
- ↑ Jump up to: 1.0 1.1 Kuchin S, et al. (2002) Snf1 protein kinase and the repressors Nrg1 and Nrg2 regulate FLO11, haploid invasive growth, and diploid pseudohyphal differentiation. Mol Cell Biol 22(12):3994-4000 SGD PMID 12024013
- ↑ Jump up to: 2.0 2.1 2.2 2.3 2.4 2.5 Vyas VK, et al. (2001) Interaction of the repressors Nrg1 and Nrg2 with the Snf1 protein kinase in Saccharomyces cerevisiae. Genetics 158(2):563-72
SGD PMID 11404322 Cite error: Invalid
<ref>tag; name "S000060795" defined multiple times with different content Cite error: Invalid<ref>tag; name "S000060795" defined multiple times with different content Cite error: Invalid<ref>tag; name "S000060795" defined multiple times with different content Cite error: Invalid<ref>tag; name "S000060795" defined multiple times with different content Cite error: Invalid<ref>tag; name "S000060795" defined multiple times with different content - ↑ Jump up to: 3.0 3.1 3.2 3.3 Vyas VK, et al. (2003) Snf1 kinases with different beta-subunit isoforms play distinct roles in regulating haploid invasive growth. Mol Cell Biol 23(4):1341-8 SGD PMID 12556493
- ↑ Jump up to: 4.0 4.1 4.2 4.3 submitted by Valmik K. Vyas on 2003-03-27
- ↑ Jump up to: 5.0 5.1 5.2 5.3 5.4 5.5 submitted by Valmik K. Vyas on 2003-02-04
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
- Pages with reference errors
- ORF
- ORF, Verified
- Topic:Alleles, Strains, and Phenotypes
- Topic:Alleles, Strains, and Phenotypes:Multiple Knockout Strains
- Phenotype:Loss of function (Null)
- Topic:Alleles, Strains, and Phenotypes:Overexpression
- Phenotype:Dominant
- Phenotype:Gain of function
- Topic:Interactions
- Topic:Interactions:Genetic
- Genetic Interaction with Snf1
- Topic:Interactions:Physical
- Physical Interactions with Snf1
- Topic:Interactions:Two Hybrid
- Two Hybrid Interactions with Snf1
- Topic:Protein Details
- Topic:Protein Details:Protein Function/Process
