Difference between revisions of "YBR043C"
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{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000247 YBR043C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''QDR3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''QDR3 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr II:323945..321876 | |nowrap| Chr II:323945..321876 | ||
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+ | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000247 | ||
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− | '''Description of | + | '''Description of YBR043C:''' Multidrug transporter of the major facilitator superfamily, has a role in polyamine homeostasis; expression is upregulated under polyamine stress; required for resistance to quinidine, barban, cisplatin, and bleomycin<ref name='S000061823'>Rieger KJ, et al. (1999) Chemotyping of yeast mutants using robotics. Yeast 15(10B):973-86 {{SGDpaper|S000061823}} PMID 10407277</ref><ref name='S000142425'>Teixeira MC, et al. (2010) Yeast response and tolerance to polyamine toxicity involving the drug:H+ antiporter Qdr3 and the transcription factors Yap1 and Gcn4. Microbiology () {{SGDpaper|S000142425}} PMID 21148207</ref><ref name='S000080433'>Tenreiro S, et al. (2005) The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun 327(3):952-9 |
− | + | {{SGDpaper|S000080433}} PMID 15649438</ref> | |
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 07:45, 23 January 2012
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Systematic name | YBR043C |
Gene name | QDR3 |
Aliases | AQR2 |
Feature type | ORF, Verified |
Coordinates | Chr II:323945..321876 |
Primary SGDID | S000000247 |
Description of YBR043C: Multidrug transporter of the major facilitator superfamily, has a role in polyamine homeostasis; expression is upregulated under polyamine stress; required for resistance to quinidine, barban, cisplatin, and bleomycin[1][2][3]
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References
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- ↑ Rieger KJ, et al. (1999) Chemotyping of yeast mutants using robotics. Yeast 15(10B):973-86 SGD PMID 10407277
- ↑ Teixeira MC, et al. (2010) Yeast response and tolerance to polyamine toxicity involving the drug:H+ antiporter Qdr3 and the transcription factors Yap1 and Gcn4. Microbiology () SGD PMID 21148207
- ↑ Tenreiro S, et al. (2005) The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun 327(3):952-9 SGD PMID 15649438
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