YBR043C

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Systematic name YBR043C
Gene name QDR3
Aliases AQR2
Feature type ORF, Verified
Coordinates Chr II:323945..321876
Primary SGDID S000000247


Description of YBR043C: Multidrug transporter of the major facilitator superfamily, has a role in polyamine homeostasis; expression is upregulated under polyamine stress; required for resistance to quinidine, barban, cisplatin, and bleomycin[1][2][3]




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References

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  1. Rieger KJ, et al. (1999) Chemotyping of yeast mutants using robotics. Yeast 15(10B):973-86 SGD PMID 10407277
  2. Teixeira MC, et al. (2010) Yeast response and tolerance to polyamine toxicity involving the drug:H+ antiporter Qdr3 and the transcription factors Yap1 and Gcn4. Microbiology () SGD PMID 21148207
  3. Tenreiro S, et al. (2005) The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun 327(3):952-9 SGD PMID 15649438

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