Difference between revisions of "YAL048C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000046 YAL048C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GEM1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GEM1 '' | ||
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| − | '''Description of YAL048C:''' | + | '''Description of YAL048C:''' Outer mitochondrial membrane GTPase, subunit of the ERMES complex; potential regulatory subunit of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; ortholog of metazoan Miro GTPases<ref name='S000079817'>Frederick RL, et al. (2004) Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway. J Cell Biol 167(1):87-98 {{SGDpaper|S000079817}} PMID 15479738</ref><ref name='S000147272'>Kornmann B, et al. (2011) The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections. Proc Natl Acad Sci U S A 108(34):14151-6 {{SGDpaper|S000147272}} PMID 21825164</ref><ref name='S000146948'>Stroud DA, et al. (2011) Composition and Topology of the Endoplasmic Reticulum-Mitochondria Encounter Structure. J Mol Biol () {{SGDpaper|S000146948}} PMID 21945531</ref><ref name='S000039821'>Wolff AM, et al. (1999) The open reading frame YAL048c affects the secretion of proteinase A in S. cerevisiae. Yeast 15(5):427-34 |
{{SGDpaper|S000039821}} PMID 10220001</ref> | {{SGDpaper|S000039821}} PMID 10220001</ref> | ||
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YAL048C |
| Gene name | GEM1 |
| Aliases | GON1 |
| Feature type | ORF, Verified |
| Coordinates | Chr I:54789..52801 |
| Primary SGDID | S000000046 |
Description of YAL048C: Outer mitochondrial membrane GTPase, subunit of the ERMES complex; potential regulatory subunit of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; ortholog of metazoan Miro GTPases[1][2][3][4]
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References
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- Jump up ↑ Frederick RL, et al. (2004) Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway. J Cell Biol 167(1):87-98 SGD PMID 15479738
- Jump up ↑ Kornmann B, et al. (2011) The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections. Proc Natl Acad Sci U S A 108(34):14151-6 SGD PMID 21825164
- Jump up ↑ Stroud DA, et al. (2011) Composition and Topology of the Endoplasmic Reticulum-Mitochondria Encounter Structure. J Mol Biol () SGD PMID 21945531
- Jump up ↑ Wolff AM, et al. (1999) The open reading frame YAL048c affects the secretion of proteinase A in S. cerevisiae. Yeast 15(5):427-34 SGD PMID 10220001
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