Difference between revisions of "YAL044C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YAL044C YAL044C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000042 YAL044C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''GCV3 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''GCV3 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr I:58463..57951
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|nowrap| Chr I:58462..57950
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000042
 
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'''Description of {{PAGENAME}}:''' H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm<ref name='S000075481'>Gelling CL, et al. (2004) Identification of a novel one-carbon metabolism regulon in Saccharomyces cerevisiae. J Biol Chem 279(8):7072-81 {{SGDpaper|S000075481}} PMID 14645232</ref><ref name='S000056431'>Piper MD, et al. (2000) Regulation of the balance of one-carbon metabolism in Saccharomyces cerevisiae. J Biol Chem 275(40):30987-95
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'''Description of YAL044C:''' H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; also required for all protein lipoylation; expression is regulated by levels of 5,10-methylene-THF<ref name='S000075481'>Gelling CL, et al. (2004) Identification of a novel one-carbon metabolism regulon in Saccharomyces cerevisiae. J Biol Chem 279(8):7072-81 {{SGDpaper|S000075481}} PMID 14645232</ref><ref name='S000056431'>Piper MD, et al. (2000) Regulation of the balance of one-carbon metabolism in Saccharomyces cerevisiae. J Biol Chem 275(40):30987-95 {{SGDpaper|S000056431}} PMID 10871621</ref><ref name='S000130792'>Schonauer MS, et al. (2009) Lipoic Acid synthesis and attachment in yeast mitochondria. J Biol Chem 284(35):23234-42
  {{SGDpaper|S000056431}} PMID 10871621</ref>
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  {{SGDpaper|S000130792}} PMID 19570983</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YAL044C
Gene name GCV3
Aliases
Feature type ORF, Verified
Coordinates Chr I:58462..57950
Primary SGDID S000000042


Description of YAL044C: H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; also required for all protein lipoylation; expression is regulated by levels of 5,10-methylene-THF[1][2][3]




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References

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  1. Gelling CL, et al. (2004) Identification of a novel one-carbon metabolism regulon in Saccharomyces cerevisiae. J Biol Chem 279(8):7072-81 SGD PMID 14645232
  2. Piper MD, et al. (2000) Regulation of the balance of one-carbon metabolism in Saccharomyces cerevisiae. J Biol Chem 275(40):30987-95 SGD PMID 10871621
  3. Schonauer MS, et al. (2009) Lipoic Acid synthesis and attachment in yeast mitochondria. J Biol Chem 284(35):23234-42 SGD PMID 19570983

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