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Systematic name YAL044C
Gene name GCV3
Feature type ORF, Verified
Coordinates Chr I:58462..57950
Primary SGDID S000000042

Description of YAL044C: H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; also required for all protein lipoylation; expression is regulated by levels of 5,10-methylene-THF[1][2][3]


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  1. Gelling CL, et al. (2004) Identification of a novel one-carbon metabolism regulon in Saccharomyces cerevisiae. J Biol Chem 279(8):7072-81 SGD PMID 14645232
  2. Piper MD, et al. (2000) Regulation of the balance of one-carbon metabolism in Saccharomyces cerevisiae. J Biol Chem 275(40):30987-95 SGD PMID 10871621
  3. Schonauer MS, et al. (2009) Lipoic Acid synthesis and attachment in yeast mitochondria. J Biol Chem 284(35):23234-42 SGD PMID 19570983

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