Difference between revisions of "YOR359W"

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|nowrap| Chr XV:1011187..1012758
 
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==Community Commentary==
 
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==References==
 
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Revision as of 07:18, 30 January 2007

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Systematic name YOR359W
Gene name VTS1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:1011187..1012758


Description of YOR359W: Post-transcriptional gene regulator, RNA-binding protein containing a SAM domain; shows genetic interactions with Vti1p, which is a v-SNARE involved in cis-Golgi membrane traffic[1][2]




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Community Commentary

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Protein Details

Nucleic Acid Binding

YOR359W binds RNA Specific binding to an RNA stem-loop of CNGGN motif. Involved in CCR4 mediated deadnylation and degradation of targets. [3] [4]


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References

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  1. Oberstrass FC, et al. (2006) Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat Struct Mol Biol 13(2):160-7 SGD PMID 16429156
  2. Dilcher M, et al. (2001) Genetic interactions with the yeast Q-SNARE VTI1 reveal novel functions for the R-SNARE YKT6. J Biol Chem 276(37):34537-44 SGD PMID 11445562
  3. Aviv T, et al. (2003) The RNA-binding SAM domain of Smaug defines a new family of post-transcriptional regulators. Nat Struct Biol 10(8):614-21 SGD PMID 12858164
  4. submitted by Tzvi Aviv on 2003-10-10

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