Difference between revisions of "YBL078C"
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| − | '''Description of YBL078C:''' Component of autophagosomes and Cvt vesicles; undergoes conjugation to phosphatidylethanolamine (PE); Atg8p-PE is anchored to membranes, is involved in phagophore expansion, and may mediate membrane fusion during autophagosome formation<ref name='S000059720'>Ichimura Y, et al. (2000) A ubiquitin-like system mediates protein lipidation. Nature 408(6811):488-92 {{SGDpaper|S000059720}} PMID 11100732</ref><ref name='S000059897'>Kirisako T, et al. (2000) The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 151(2):263-76 {{SGDpaper|S000059897}} PMID 11038174</ref><ref name='S000123418'>Nakatogawa H, et al. (2007) Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion. Cell 130(1):165-78 {{SGDpaper|S000123418}} PMID 17632063</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 {{SGDpaper|S000051835}} PMID 8224160</ref><ref name='S000127124'>Xie Z, et al. (2008) Atg8 Controls Phagophore Expansion during Autophagosome Formation. Mol Biol Cell 19(8):3290-8 | + | '''Description of YBL078C:''' Component of autophagosomes and Cvt vesicles; undergoes conjugation to phosphatidylethanolamine (PE); Atg8p-PE is anchored to membranes, is involved in phagophore expansion, and may mediate membrane fusion during autophagosome formation<ref name='S000059720'>Ichimura Y, et al. (2000) A ubiquitin-like system mediates protein lipidation. Nature 408(6811):488-92 {{SGDpaper|S000059720}} PMID 11100732</ref><ref name='S000059897'>Kirisako T, et al. (2000) The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 151(2):263-76 {{SGDpaper|S000059897}} PMID 11038174</ref><ref name='S000146892'>Nair U, et al. (2011) SNARE proteins are required for macroautophagy. Cell 146(2):290-302 {{SGDpaper|S000146892}} PMID 21784249</ref><ref name='S000123418'>Nakatogawa H, et al. (2007) Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion. Cell 130(1):165-78 {{SGDpaper|S000123418}} PMID 17632063</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 {{SGDpaper|S000051835}} PMID 8224160</ref><ref name='S000127124'>Xie Z, et al. (2008) Atg8 Controls Phagophore Expansion during Autophagosome Formation. Mol Biol Cell 19(8):3290-8 |
{{SGDpaper|S000127124}} PMID 18508918</ref> | {{SGDpaper|S000127124}} PMID 18508918</ref> | ||
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Revision as of 13:05, 5 October 2011
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBL078C |
| Gene name | ATG8 |
| Aliases | APG8, AUT7, CVT5 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:80731..80378 |
| Primary SGDID | S000000174 |
Description of YBL078C: Component of autophagosomes and Cvt vesicles; undergoes conjugation to phosphatidylethanolamine (PE); Atg8p-PE is anchored to membranes, is involved in phagophore expansion, and may mediate membrane fusion during autophagosome formation[1][2][3][4][5][6]
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References
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- ↑ Ichimura Y, et al. (2000) A ubiquitin-like system mediates protein lipidation. Nature 408(6811):488-92 SGD PMID 11100732
- ↑ Kirisako T, et al. (2000) The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 151(2):263-76 SGD PMID 11038174
- ↑ Nair U, et al. (2011) SNARE proteins are required for macroautophagy. Cell 146(2):290-302 SGD PMID 21784249
- ↑ Nakatogawa H, et al. (2007) Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion. Cell 130(1):165-78 SGD PMID 17632063
- ↑ Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160
- ↑ Xie Z, et al. (2008) Atg8 Controls Phagophore Expansion during Autophagosome Formation. Mol Biol Cell 19(8):3290-8 SGD PMID 18508918
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