Difference between revisions of "YOL021C"
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|nowrap| Chr XV:285427..282422 | |nowrap| Chr XV:285427..282422 | ||
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==Community Commentary== | ==Community Commentary== | ||
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Revision as of 08:18, 30 January 2007
Share your knowledge...Edit this entry! <protect>
Systematic name | YOL021C |
Gene name | DIS3 |
Aliases | RRP44 |
Feature type | ORF, Verified |
Coordinates | Chr XV:285427..282422 |
Description of YOL021C: Nucleolar exosome component, involved in rRNA processing and RNA degradation, binds Gsp1p/Ran and enhances the GEF activity of Srm1p, implicated in mitotic control, homologous to the E. coli RNase R of the RNase II family[1][2][3][4][5]
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Contents
Community Commentary
About Community Commentary. Please share your knowledge!
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References
See Help:References on how to add references
- ↑ Suzuki N, et al. (2001) The Saccharomyces cerevisiae small GTPase, Gsp1p/Ran, is involved in 3' processing of 7S-to-5.8S rRNA and in degradation of the excised 5'-A0 fragment of 35S pre-rRNA, both of which are carried out by the exosome. Genetics 158(2):613-25 SGD PMID 11404326
- ↑ Chekanova JA, et al. (2000) Poly(A) tail-dependent exonuclease AtRrp41p from Arabidopsis thaliana rescues 5.8 S rRNA processing and mRNA decay defects of the yeast ski6 mutant and is found in an exosome-sized complex in plant and yeast cells. J Biol Chem 275(42):33158-66 SGD PMID 10930416
- ↑ Shiomi T, et al. (1998) Human dis3p, which binds to either GTP- or GDP-Ran, complements Saccharomyces cerevisiae dis3. J Biochem (Tokyo) 123(5):883-90 SGD PMID 9562621
- ↑ Mitchell P, et al. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases. Cell 91(4):457-66 SGD PMID 9390555
- ↑ Noguchi E, et al. (1996) Dis3, implicated in mitotic control, binds directly to Ran and enhances the GEF activity of RCC1. EMBO J 15(20):5595-605 SGD PMID 8896453
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