Difference between revisions of "YPL127C"
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==Community Commentary== | ==Community Commentary== | ||
Revision as of 10:51, 24 January 2007
Share your knowledge...Edit this entry!
| Systematic name | YPL127C | |
| Gene name | HHO1 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XVI:309603..308827 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YPL127C: Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation[1][2][3][4][5][6][7][8]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Alleles, Strains, and Phenotypes
Complete Deletion
Strain Background: S288c
Genotype: BQS238: MATalfa, ura3-52, leu2-3,112, ade2-101, suc2-delta9, gal2, hho1delta0, pRB58
Phenotype(s): No Phenotype, Deletion of HHO1 has no effect on nucleosome positioning, Viable
Hho1p has no effect on nucleosome positioning in yeast. [6] [9]
DNA and RNA Details
Other DNA and RNA Details
Other Topic: Nucleosome positioning
We analyzed a chromatin region of the yeast Chromosome (Chr) IX, in which there are two closely packed open reading frames (ORFs), POT1 and YIL161w. This locus shows a regular ladder of 13 stochastically positioned nucleosomes, which is unaffected by the absence of the HHO1 gene. This suggests that histone H1 has no effect on nucleosome positioning in yeast. [6] [9]
References
See Help:References on how to add references
- ↑ Downs JA, et al. (2003) Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone. Mol Cell 11(6):1685-92 SGD PMID 12820979
- ↑ Freidkin I and Katcoff DJ (2001) Specific distribution of the Saccharomyces cerevisiae linker histone homolog HHO1p in the chromatin. Nucleic Acids Res 29(19):4043-51 SGD PMID 11574687
- ↑ Landsman D (1996) Histone H1 in Saccharomyces cerevisiae: a double mystery solved? Trends Biochem Sci 21(8):287-8 SGD PMID 8772381
- ↑ Hellauer K, et al. (2001) Decreased expression of specific genes in yeast cells lacking histone H1. J Biol Chem 276(17):13587-92 SGD PMID 11278859
- ↑ Escher D and Schaffner W (1997) Gene activation at a distance and telomeric silencing are not affected by yeast histone H1. Mol Gen Genet 256(4):456-61 SGD PMID 9393443
- ↑ 6.0 6.1 6.2 Puig S, et al. (1999) Stochastic nucleosome positioning in a yeast chromatin region is not dependent on histone H1. Curr Microbiol 39(3):168-72 SGD PMID 10441732
- ↑ Patterton HG, et al. (1998) The biochemical and phenotypic characterization of Hho1p, the putative linker histone H1 of Saccharomyces cerevisiae. J Biol Chem 273(13):7268-76 SGD PMID 9516420
- ↑ Ushinsky SC, et al. (1997) Histone H1 in Saccharomyces cerevisiae. Yeast 13(2):151-61 SGD PMID 9046096
- ↑ 9.0 9.1 submitted by Jose E. Perez-Ortin on 2004-05-27
See Help:Categories on how to add the wiki page for this gene to a Category
- ORF
- ORF, Verified
- Topic:Alleles, Strains, and Phenotypes
- Topic:Alleles, Strains, and Phenotypes:Complete Deletion
- Phenotype:No Phenotype
- Phenotype:Deletion of HHO1 has no effect on nucleosome positioning
- Phenotype:Viable
- Topic:DNA and RNA Details
- Topic:DNA and RNA Details:Other DNA and RNA Details
- Topic:Nucleosome positioning
